When I had both chronic NE overload from an overactive autoimmune disease and horrendous glutamate overstimulation because of the specific nature of the autoimmune disease, I never slept more than 2 hours a night (even with heavy sleeping meds) for months at a time over a three year period. It is not a combination to fool with. If both are strongly active at the same time they will cripple a person physically, mentally, and emotionally. I would advise trying to figure which one is most severe and trying to do something about it asap. Relying on raising glutathione levels is like using a beebee gun to take on a Sherman tank if one or both of those problems are in play, at least based on my own experiences.