Hi I just wondered how many people with ME/CFS have family with immune problems, either autoimmune or allergies? My mum had severe asthma and loads of allergies, as well as eczema. In fact she died of an asthma attack aged 24 and she was always getting lung infections that put her in hospital. My gran also had rheumatoid arthritis that started when she was in her early 30's and I would get joint pain as a child long before the ME but I don't have rheumatoid arthritis. I have eczema and asthma like my mum and had allergies before the ME. I have always thought my mum played a part in me getting ME because I inherited her genes. Doctor Myhill says I have a twitchy immune system because I have always been vulnerable to allergy. I also have multiple chemical sensitivity and EMF sensitivity and they can cause PEM for me just as much as exertion. I definitely think it's genetic!