I have had CFS and Fibro a long time. I am planning to start allergy shots for dust mites (severe allergy), and was wanting any input from others. On the one hand, I am thinking, why go through all these shots for years (probably 3-5 years or more) when I will probably still be tired all the time? On the other hand, it seems worth it to have a little less symptoms? I have food sensitivities/intolerances/allergies too, and am highly sensitive to chemicals (MCS, maybe not formally diagnosed, I don't know what the allergist wrote in his report), and am allergic to some trees/grasses/etc. Dust mites was the main allergy based on the doc's skin prick test but I feel that the way MDs test misses plenty of problems. Do I need to ask for anything special in the preparation? Should I watch out for anything because of my MCS and CFS? Thank you all. ... read someone else said her arm burned all day & some other negative effects... I don't know what to think... maybe I should try one or two and see how I react... seems like a lot to commit to years and years of it. Most people get the symptoms back if they stop and if they miss one for the first many months or years, that's a setback, as they have to go to a lower dose again... ... on the plus side, I read that (according to allergists) a major allergy could "cause" the others. So if I treated this one major allergy, maybe I'd be less sensitive in general?