Since becoming a bodyworker, I discovered that alot of people with knee problems tended to keep their legs straight and their knees locked. I have never done this and accredit it to having decent knees. I think what i failed to realise is, i do it more because i don't become flexible - no matter how much stretching i do. I thought i'd drop this here because i know alot of people are struggling with pain in their body and how i've found some effective supplements that help me. Collagen - since taking this, i stand straight with knees locked, so my hamstrings have actually released quite a bit from that. (tight hamstrings for those not in bodywork are a keen indicator of depression, i think it may have to do with the processing that goes on and the shut down of systems but thats my reasoning) So my muscles/tendons have lengthened somewhat - being 6'3 this is quite important. Evening Primrose oil and D3 - lubrication/hydration is very important for the body. As it seems a good majority of CFS patients struggle with dry eyes. Fish oil never seemed to have any lasting effect for me. Reading up on the methylation stuff, it seems my type is more suited to evening primrose. Though again, i'll point out different versions of fish oil work for different people. The vitamin d is going alot better with the zinc i'm taking to give me more pallor. Glucosamine, Chondroiton, MSM - this stuff worked like a charm, however i'm sensitive to something in it, possibly the fact that its converted into sugar form and i struggle with sugars. However, i moved onto collagen instead, which is working well. I remember when i was five and i ended up in hospital for two months because my legs stopped working. I had cellulitis and went to two hospitals, if my mother had left me at the first i would have died as the infection was travelling fast up my leg.