Home care is the theme for Severe ME Day on August 8th
Why should home care be the theme on Understanding and Remembrance Day for Severe ME on August 8? Helen Brownlie of the 25% ME Group has written an explanation for Phoenix Rising ...
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Infection of XC Cells by MLVs Is Endosome-Dependent but Acidific-Independent

Discussion in 'XMRV Research and Replication Studies' started by Jemal, Oct 26, 2011.

  1. Jemal

    Jemal Senior Member

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    This is a study from Japan that talks about XMRV/MLV's. It was published 12 oct.
    It's all gibberish to me... I can understand some of the words, but that's about it. And it's in English, not even in Japanese :D
    Does anyone understand what they are talking about here?

    http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0026180
     
  2. Tony Mach

    Tony Mach Show me the evidence.

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    Upper Palatinate, Bavaria
    I'm no expert, but to me this sounds like they looked how P/X/MLV/XMRV viruses infects certain cells. Specially what influcence the pH of the endosome (how "acid" a certain part of the cell is) is with regards to an enzym called "cathepsin protease". Don't know if this is an viral enzym, or a human enzym though, and what role it plays with regards to XMRV.

    Molecular mini-micro-pico-research at its best, I presume. It is like the joke about the three blind men, who try to describe what an elephant is: "It is a tail!", "No, it is a trunk!" and "No, it is a leg!". Only here, they looked at an hair of the elephant.

    Doesn't matter. It's a blind alley with regards to ME/CFS.
     
  3. Jemal

    Jemal Senior Member

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    Thanks for your reply Tony, it makes some more sense now. I am not so sure this is a blind alley, though.
     
  4. Deatheye

    Deatheye Senior Member

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    http://en.wikipedia.org/wiki/Cathepsin
     

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