I recently started beta glucan at my doctor's suggestion (Kendal Stewart). He and my nutritionist think a lot of my problems are from infections and viruses. I've taken great immune-boosting and natural antiviral and antibacterial supplements for years, but have not gotten much symptom relief from them. I also take Valacyclovir. I started taking the Neurobiologix Immune Restore brand of beta glucan about 3 weeks ago: http://www.neurobiologix.com/product-p/809.htm What I'm noticing is that I'm slowly able to add supplements and increase dosages of current supplements without having a negative sleep effect. This is huge for me. As an example, I have such a sensitive system that I've only been able to take 1/8th of a tsp. of lecithin over the last couple of years. A full dose is 3 tsp. I have taken the full dose before, and it greatly boosts my energy and mood, maybe because of the dopamine uplift from the phosphatidylcholine. However, I haven't been able to take that dose because it wreaks havoc with my sleep. Since taking the beta glucan, I've slowly built up to 1/2 tsp. of lecithin. I'm hoping I can increase that over time. Before beta glucan even 1/4 tsp. wrecked my sleep. I've been able to take a little more ribose and some supplements such as zinc that I couldn't take at all before beta glucan. My nutritionist thinks my increased tolerance might be because the beta glucan is improving my TH1:TH2 balance. I was scared to start taking beta glucan because I had done a search in the forum and found someone who had a truly godawful response that lasted a long time after he stopped. My nutritionist said that small numbers of people can't take it because it increases autoimmune symptoms for them. Anyway, I'm really tickled at this progress.