New era for ME/CFS research as top cytokine study attracts media headlines
The immune systems of patients who have recently developed ME/CFS look markedly different from those who have been ill for much longer, according to a major new study from Drs. Ian Lipkin and Mady Hornig at Columbia University. This shift in immune function hadn’t been seen before.
Discuss the article on the Forums.

In vitro assembly of virus-like particles of a Gammaretrovirus (XMRV)

Discussion in 'XMRV Research and Replication Studies' started by Jemal, Nov 17, 2011.

  1. Jemal

    Jemal Senior Member

    Messages:
    1,031
    Likes:
    60
    I have no idea what it means...

    http://jvi.asm.org/content/early/2011/11/09/JVI.05564-11.abstract?related-urls=yes&legid=jvi;JVI.05564-11v1
     
  2. Tony Mach

    Tony Mach Show me the evidence.

    Messages:
    146
    Likes:
    34
    Upper Palatinate, Bavaria
    As far as I understand, they studied how the individual pieces of a XMRV virus ("structural proteins") fall together ("are assembled") to form virus-like particles (I guess either incomplete viruses or a intermediate step to a full virus but I could be wrong). They seem to have found differences in the assembly to other Gammaretroviruses whether these differences are big or subtle, I can't tell.

    If XMRV were a human pathogen, this could offer clues how to block this step in virus formation. As it stands, XMRV is not a human pathogen so this only helps further the understanding of viruses in general.
     
  3. Bob

    Bob

    Messages:
    9,853
    Likes:
    16,575
    South of England
    I'm not sure exactly what it means either. Like Tony said, it seems to be exploring the way that immature viral particles combine to form mature viruses. But I can't work out what the significance might be from reading only this abstract.
     
  4. Enid

    Enid Senior Member

    Messages:
    3,309
    Likes:
    844
    UK
    Whatever it does mean, it is good to see advances in the understanding of viral behaviours going on. (I'm not a scientist though).
     

See more popular forum discussions.

Share This Page