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In vitro assembly of virus-like particles of a Gammaretrovirus (XMRV)

Discussion in 'XMRV Research and Replication Studies' started by Jemal, Nov 17, 2011.

  1. Jemal

    Jemal Senior Member

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    I have no idea what it means...

    http://jvi.asm.org/content/early/2011/11/09/JVI.05564-11.abstract?related-urls=yes&legid=jvi;JVI.05564-11v1
  2. Tony Mach

    Tony Mach Show me the evidence.

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    Upper Palatinate, Bavaria
    As far as I understand, they studied how the individual pieces of a XMRV virus ("structural proteins") fall together ("are assembled") to form virus-like particles (I guess either incomplete viruses or a intermediate step to a full virus but I could be wrong). They seem to have found differences in the assembly to other Gammaretroviruses whether these differences are big or subtle, I can't tell.

    If XMRV were a human pathogen, this could offer clues how to block this step in virus formation. As it stands, XMRV is not a human pathogen so this only helps further the understanding of viruses in general.
  3. Bob

    Bob

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    England, UK
    I'm not sure exactly what it means either. Like Tony said, it seems to be exploring the way that immature viral particles combine to form mature viruses. But I can't work out what the significance might be from reading only this abstract.
  4. Enid

    Enid Senior Member

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    Whatever it does mean, it is good to see advances in the understanding of viral behaviours going on. (I'm not a scientist though).

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