Its mentioned alot about mixing up the dose of immune mods as this helps to keep the treatment working by reducing tolerance etc. I was thinking of the high and low dose days and really the low dose days probably wouldnt have any affect at all, so im thinking why bother. Maybe we should just not take it those days. Initially one has to slowly build up to what they can tolerate but say when one gets to 6 tabs a day, i think it would be just as affective to use it every second day or mon/wed/fri only for 2 months then one month off. I think the low dose days would be inaffective and just adds to the cost of treatment, plus having more off days would be better at reducing tolerance to the affects of immune mods. Another immune mod i have used cycloferron, it is recommended use is every second to third day after the initial 2-3 days in a row of use. cheers!!!