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Immunology conference today in Chicago

Discussion in 'General ME/CFS News' started by Kati, Jun 14, 2017.

  1. Kati

    Kati Patient in training

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    https://www.eventscribe.com/2017/FOCIS/agenda.asp?h=Full Schedule

    There will be 4 hours scientific presentation titled 'Insights into the Immunology of Chronic Fatigue Syndrome' today in Chicago, sponsored by NIH (NIAID) and featuring some of the proeminent researchers in the field. Here is further info upon finding it on the schedule:

    Member Society Symposia

    Insights into the Immunology of Chronic Fatigue Syndrome
    Wednesday, June 14
    12:45 PM - 4:45 PM


    Sponsored By:
    [​IMG]


    Myalgic encephalomyelitis /chronic fatigue syndrome (ME/CFS) is a debilitating and complex disorder that severely impacts the life of ~2 million Americans. There is no documented cause of ME/CFS, it is difficult to diagnose, and there are no specific biomarkers nor diagnostic testing available currently. Multiple recent ME/CFS expert panels have recommended multidisciplinary, novel approaches to gain a better understanding of ME/CFS. This symposium will bring together immunologists working in the ME/CFS field to review progress of immunological studies and foster collaborations on biomarker discovery, immune mechanisms and potential therapeutic development.

    Chair:
    Joseph Breen, PhD, National Institutes of Health

    Program:

    12:45p.m. Welcome and Objectives
    Joseph Breen, PhD, National Institutes of Health and Vicky Whittemore, PhD, National Institute of Neurological Disorders and Stroke

    12:50 p.m. The Public Health Problem of ME/CFS
    Elizabeth Unger, MD, Centers for Disease Control and Prevention

    1:15 p.m. Evidence of T-Cell activity in ME/CFS
    Mark Davis, PhD, Stanford University

    1:45 p.m. Immunological characterisation of ME/CFS cases and controls from the UK ME/CFS Biobank
    Eleanor Riley, PhD, University of London

    2:35 p.m. - Coffee break

    2:55 p.m. Pathobiology of ME/CFS
    Ian Lipkin, MD, Columbia University

    3:35 p.m. Circulating Cytokine Signatures Associated with ME/CFS Severity and Duration
    Jose Montoya, MD, Stanford University

    4:15 p.m. Question/Answer Forum
    All speakers

    Learning Objectives:
    • This half‐day symposium will provide a forum for experts in the immunology of ME/CFS to present the current state of the science to key clinical immunology stakeholders. These interactions should stimulate new approaches to decipher the mechanistic and immunological underpinnings of ME/CFS. Such collaborative efforts will open new research avenues and potential clinical solutions to combat ME/CFS.


    Footnote: I do not believe there is webcasting for this, it would be nice if it was.
     
    ghosalb, MEMum, Aroa and 17 others like this.
  2. BurnA

    BurnA Senior Member

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    Yes would like to know what Mark Davis is saying about T cells, I don't believe we have heard much on that before.
     
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  3. msf

    msf Senior Member

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    Lipkin´s title seems rather grandiose, I wonder if he is going to outline his theory of ME.
     
  4. Gemini

    Gemini Senior Member

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    I submitted a request to the Trans-NIH ME/CFS Working Group they make a video, transcript and/or slides available of all the presentations, including Mark Davis', if possible.
     
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  5. Gemini

    Gemini Senior Member

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    Reply received today from NINDS:

    Thank you for your inquiry about the "Insights into the Immunology of CFS" session of the recent FOCiS Conference. The FOCIS session was not videocast, and the organizers are not distributing a transcript or slides. However, information from the session will be summarized at the next Trans-NIH ME/CFS Working Group telebriefing on July 10. Additional information about the telebriefing will be distributed to the Trans-NIH ME/CFS Information list when it is closer to the event date.

    Sincerely,
    Marian Emr
    Director, Office of Communications and Public Liaison
    National Institute of Neurological Disorders and Stroke
    on behalf of the Trans-NIH ME/CFS Working Group
     
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  6. Gemini

    Gemini Senior Member

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    Have requested Columbia University post a transcript and/or slides from Dr. Lipkin's "Pathobiology of ME/CFS" presentation on the website that summarizes findings of his recent ME/CFS studies.
     
    Last edited: Jun 19, 2017
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  7. charles shepherd

    charles shepherd Senior Member

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    Professor Eleanor Riley is an immunologist at the London School of Hygiene and Tropical Medicine and works with the ME Biobank team which is based there.

    The ME Biobank forms a sub-biobank within the UCL Biobank at the Royal Free Hospital

    Professor Riley was presenting results from an immunological study study that was carried out using blood samples from the ME Biobank

    ME Biobank:http://cureme.lshtm.ac.uk

    Professor Eleanor Riley:https://www.lshtm.ac.uk/aboutus/people/riley.eleanor

    NIH grant for ME Biobank studiies:http://grantome.com/grant/NIH/R01-AI103629-01A1


    Public Health Relevance
    This is, to our knowledge, the first longitudinal study of ME/CFS to incorporate both mild and severe cases, age, sex, and residence-matched Multiple Sclerosis (MS) and healthy controls, and to incorporate virological, immunological and gene expression data into the same study. There is a clear need for research in these areas, and the inclusion of severe cases using home visits will allow for research on a subset of patients often neglected in ME/CFS studies. Because approximately 1-4 million Americans have ME/CFS, this study has the potential to impact the lives of a large patient population in the US as well as advance the state of the field in the US, UK, and globally through the potential identification of evidence related to disease etiology and pathophysiology as well as disease subtypes and biomarkers, revealing potential routes for treatment.



    Dr Charles Shepherd
    Hon Medical Adviser, MEA
    Chair - ME Biobank Steering Group
     
    Last edited: Jun 19, 2017
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  8. BurnA

    BurnA Senior Member

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    Thanks, will we be hearing more about this do you know?
     
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  9. Londinium

    Londinium

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    I'm guessing that, given this is also now being trailed on the MEA website, the results are interesting rather than a null finding? Or am I reading too much into it?

    (A totally unfair question as I realise you cannot comment :)).
     
    Last edited: Jun 20, 2017 at 10:00 AM
  10. charles shepherd

    charles shepherd Senior Member

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    At this point I'm afraid I cannot go any further than to point you back to the announcement from NIH - who are funding this longitudinal study of immune system function at the ME Biobank

    As you can see, one of the aims of the study is to find out what happens to immune system functioning during an exacerbation or relapse of ME/CFS

    The NIH study has also been obtaining data on the same aspects of immune system function in people with mild, moderate and severe ME/CFS

    This is one of the big advantages of having an ME Biobank that has blood samples from all grades of ME/CFS severity with anonymised clinical data attached

    CS
     
  11. Gemini

    Gemini Senior Member

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    @charles shepherd, thank you for your excellent work helping patients and for posting links re: this "most" important study.The schedule indicates it began in 2013 and ended in 2016,13 months ago, if I'm reading correctly.

    Do you happen to know if Prof. Riley presented "actual" study results at this Conference which covers the latest breakthroughs in immune-mediated diseases?

    Reason for asking I don't see a published paper about the study from Dr. Nacul, et al in PubMed yet. Might they be publishing soon do you know?
     
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