The Power and Pitfalls of Omics: George Davey Smith’s storming talk at ME/CFS conference
Read about the talk that stole the show at a recent ME/CFS conference in Simon McGrath's two-part blog.
Discuss the article on the Forums.
  1. PeterPositive

    PeterPositive Senior Member

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    Hello,
    is anyone familiar with this herbal product?

    [​IMG]

    My doc suggested it as a support for the immune function. I have taken it for 7-8 days and have had a worsening of constipation, drop in energy and lots of flu-like symptoms. The latter in particular is exactly what I was looking forward to avoid / eliminate :)

    It could be pure coincidence, so I stopped it for a few days and symptoms have diminished. I am planning to retry in a few days and see if those symptoms return.

    Ingredients are:

    imm-renew-ingr.png

    I am usually not a big fan of herb blends, because I typically find one (or more) ingredients that bother me (especially GI) and I can't determine which is which. Typically I prefer to test each herb individually.

    Has anyone tried this supplement?
    Any specific comments on any of the ingredients?

    Thanks
     

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  2. adreno

    adreno PR activist

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    I haven't tried this specific supplement, but I do not tolerate medicinal mushrooms, either. Astragalus I do tolerate.
     
  3. PeterPositive

    PeterPositive Senior Member

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    Indeed many are mushroom extracts.
    I remember having had problems years ago with digestive enzymes derived from aspergillus, but I have no idea what could be the problem with mushrooms in general. Maybe there is a connection / interaction with the gut bacteria...
     
  4. helen1

    helen1 Senior Member

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    I've used several of the ingredients - reishi, astragalus, lion's man and cordyceps as part of a c.pneumonia protocol. The reishi and astragalus info is from Buhner's compilation of studies. I can reference them in more detail if you want:

    Cordyceps is a systemic antibiotic, although there's some controversy over whether it's immune suppressing or stimulating and is sedating.

    Lion's mane is a another systemic antibiotic. There's pretty good evidence it's a nerve growth factor stimulator. I've seen it used in Lyme protocols to get spirochetes out of the brain as it crosses the BBB.

    Reishi is a very strong immune stimulator with evidence it increases T cells, macrophages, NK cells, is diuretic, mildly sedating, inhibits candida and herpes, mitogenic.

    Astragalus is immune stimulating especially the TH1 side and inhibits TH2. Very specific studies on this. Inhibits Cocksackie B.

    Can you see anything in here that might explain your symptoms?

    Die-off comes to mind...
     
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  5. PeterPositive

    PeterPositive Senior Member

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    Yes, that or simple coincidence, which I can't exclude.
    Today I have taken it again and no problems. Will see how it goes in the next days.

    Unfortunately the supplement doesn't provide details of the dosage of each components.

    Thanks for the detailed response!
     
  6. maryb

    maryb iherb code TAK122

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    I'm intolerant to mushrooms, come up every time I have any sort of testing, not sure why, just one of those things. If it makes you feel worse I think your body is saying noooo.
     
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  7. helen1

    helen1 Senior Member

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    @PeterPositive
    Often die-off symptoms are delayed by a day or so (from experience with my and others on c.pneu protocol) so I'm curious how you'll feel tomorrow. If you are killing off something, then that's a good thing as long as you don't overwhelm your body with both the die off and the cytokine response.
    Any idea what infections you might have?
     
  8. PeterPositive

    PeterPositive Senior Member

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    Good point.
    When I started I didn't have any symptoms for at least a couple of days... we'll see :)
     

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