A Little Poisoning Along the Road to ME/CFS
Looking at my symptoms, many of which are far less these days and some are gone, it would be easy to figure that I'd just been dealing with some heavy-duty menopausal issues.
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Igenex, lyme/TBD testing, different interpretations...

Discussion in 'Lyme Disease and Co-Infections' started by HTree, Jul 27, 2012.

  1. Paul M

    Paul M

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    Well they started me on Biaxin and Plaquenil, so that may be the antibiotic you are thinking of (Biaxin) - well hopefully haha
     
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  2. LaurieL

    LaurieL Senior Member

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  3. globalpilot

    globalpilot Senior Member

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    Ontario
    Anyone have any thoughts on the meaning of my results?

    IgM : positive for 34,39,41
    IgG: all negative
     
  4. Ema

    Ema Senior Member

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    I think Lyme is highly likely but the diagnosis should be made by an LLMD who can evaluate your symptoms along with the testing.

    Here is an excerpt from a blog post by LymeMD that explains IgM positive without IgG antibodies:

    http://lymemd.blogspot.com/2009/12/igm-question-is-it-chronic-lyme-disease.html

    Ema
     
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  5. LaurieL

    LaurieL Senior Member

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    I would say you need to make an appointment with a Lyme literate doc. More on your bands...

    There is a reason why the 31 and 34 bands are not included in the CDC's criteria, and that stems back to the Lyme vaccine.

    Again, my opinion, but I think Borrelia prevent the class switching, and lets not forget the different forms of the bacteria as well. The pleomorphism, again, IMO, in its different forms, could very well lead to more IgM. The lack of IgG, again IMO, is most likely due to the disruption of the Th1 and Th2 dependent reactions and then resulting in effects on the class switching of the B cells. This makes me think of Lyme in the T and/or B cells, disrupting differentiation, and preventing apoptosis. Resulting in continual immune dysfunction and lack of memory cells.

    Laurie
     
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  6. LaurieL

    LaurieL Senior Member

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    Ahhh....here is something from lymeneteurope.

    So, with this happening, its easier to remember why there is more IgM positive blots, versus IgG blots.
     
  7. roxie60

    roxie60 Senior Member

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    FYI, as of 10/15/13 each additional epitope test costs $100.00.
     

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