I have now looked at this file a bit http://www.imet.ie/imet_documents/BYRON_HYDE_little_red_book.pdf. I think it would be helpful if he could give more details about the missed illnesses that CFS patients usually have. What illnesses are these concretely? Only if he says this do doctors have a chance to diagnose people correctly. Also i think his proposed CFS definition doesn't make too much sense (with all due respect), because if he says CFS is being fatigued (gradual onset) and is often due to a missed major illness, then why give all these people with a missed diagnosis the label "CFS"? Fukuda, for example, would exclude all these cases where there is another illness that causes the symptoms and that seems to make more sense to me. Why give a missed diagnosis another name ("CFS")? If he is able to find a major illness, other than ME, in so many cases, he should share that with the world, so that every doctor can correctly diagnose these people and they can be separated from the ME/CFS cohort. Maybe he does that in one of his books.