http://www.alasbimnjournal.cl/alasbimn/index.php?option=com_content&task=view&id=136&Itemid=94 You may find this Dr Byron Hyde study interesting thou it isnt the study I seen in the past UNLESS the one I read in past was the final outcome of this (I clearly remember the results were 18-19% had thyriod cancer and I think it was a ME/CFS specialist who did the study). "100 patients whom I have investigated for (ME/CFS), with or without associated Fibromyalgia Syndrome (FS), I have found that 6% of these patients had thyroid malignancy. In each of these patients the diagnosis was made by ultrasonography and needle biopsy under ultrasonography. This was followed by surgical removal of the thyroid, and each case the malignancy was confirmed. These findings would suggest that 6% of the ME/CFS patients seen, or 6,000 cases per 100,000, had a confirmed thyroid malignancy. Unfortunately, these figures may be conservative since we are in the process of obtaining needle biopsies on six further cases of these first 100 patients. In addition, we have not yet performed thyroid ultrasound on all 100 cases. We are in the process of further investigation of those patients who had not yet been investigated by thyroid ultrasound. " compared to a rate of 0.5 to 3 patients per 100,000 in the general non ME/CFS population "Conclusions 1. ME/CFS patients who demonstrate the following: a.Abnormal SPECT scans involving cortex and subcortical perfusion defects, b.Thyroid malignancy, c.Whose fatigue syndrome does not recover after appropriate surgery and thyroid hormone replacement, and d.Have a tendency for cervical vertebrae pathology may constitute a chronic subgroup of ME/CFS patients. 2. ME/CFS patients should all be evaluated by thyroid ultrasound and, where appropriate, needle biopsy to rule out thyroid malignancy and other thyroid pathology. The fact that ME/CFS patients may have normal serum chemistry for TSH, FT3, FT4 and normal Microsomal and Thyroglobulin antibodies does not eliminate thyroid disease. 3. A chronic Hashimotos Encephalopathylike syndrome may be concurrent with ME/CFS patients who have thyroid malignancy or multinodular thyroid disease or other thyroid pathology and chronic subcortical & cortical brain SPECT changes. Non-recovery after thyroid malignancy surgery and adequate thyroid hormone replacement may be related to this chronic ME/CFS encephalopathy. 4. ME/CFS patients without thyroid malignancy yet with treated thyroid pathology, and who have not recovered from their fatigue syndrome, may also have a similar NeuroSPECT brain dysfunction. " .... Ive got to go and rest, I'll see I can find the one with the rates Im talking about another time for you. I think the ones with that subgroup tended to have osteroporosis too.