I am going to go to a Naturopath soon and try to get some natural thyroid hormone replacement. I forgot to pick up my Synthroid prescription and then forgot to take it for more then two weeks. I woke up today feeling better then I have in years. I thought about what was different and that was when I remembered I had forgotten my Synthroid. My thyroid is pretty low functioning. I was up to 150 mcg levothyroxine or 137 mcg synthroid (the doctor said synthroid was more powerful then levothyroxine). So I guess it is very telling that I actually feel better without any synthetic T-4 thyroid hormone at all. The doctor I am going to see uses desiccated cow thyroid. Has anyone else who also has Hashimoto's disease or a low functioning thyroid ever used desiccated cow thyroid instead of T-4 thyroid hormone replacement such as synthroid and levothyroxine? If so, did your CFS symptoms get better? If you also have fibromyalgia, did those symptoms get better also?