I did a fecal transplant for the third time using a different donor(my brother) and my constipation has not returned since. I had very compacted and tight stools before(rabbit pellets) and now I am regularly going once a day. I am still having other issues and there is reason to suspect that I may have poncets disease( a variant of reactive arthritis and tuberculosis) but my fatigue has greatly improved and this is the only change I made besides a vitamin C injection in my ass which hurt pretty bad if I do say so. There is reported articles on fecal transplants being effective for cfs sufferers so it is something you may all want to look into, I know its gross but really for everyone out there taking probiotics there is no chance anything you could ever purchase would come close the the efficacy that a fecal transplant could give. There is literally hundreds of strains of bacteria that are in stool and most are not available as probiotics(not to mention digestion of probiotics in stomach acid kills most) So I thought I would drop a line and let you all know of my success using this method. It has been close to a month since I did the treatment and it did not help the first two times I did it using my wife's stool.