physicsstudent13, i have Inflammatory Bowel Disease. I appreciate your comments but i need to address the inflammation. Prednisolone is a necessary evil. The supplements mentioned might help my liver but since i have IBD they might aggravate the inflammation. Milk thistle gives me diahhrea, Sam-E maybe when i'm in remission, NAC maybe but it's better to support methylation to increase glutathione. camas, thanks for your positive thoughts... i hope they will manifest. Pred is now at 15mg / day.