New Atmosphere, New Vision: Gibson and Whittemore Kick Off Invest in ME Conference 2016
Mark Berry reports on Dr. Gibson's introduction and Dr. Whittemore's keynote speech, at the 11th Invest in ME International ME Conference in London.
Discuss the article on the Forums.

Human Ebola virus infection results in substantial immune activation

Discussion in 'Other Health News and Research' started by Kati, Mar 10, 2015.

  1. Kati

    Kati Patient in training

    Messages:
    5,466
    Likes:
    19,617
    http://www.pnas.org/content/early/2015/03/05/1502619112.abstract.html?etoc


    Does this immune reaction remind you of anything? Funny how it goes. If you got Ebola, they got a special care plan for you. If you got ME/CFS/SEID, you're not special at all, and why would you get that testing for? ... (Paragraphs were made up to make reading the text easier)
     
    Last edited: Mar 10, 2015
    Jammy88, Valentijn and rosie26 like this.
  2. Bob

    Bob

    Messages:
    10,703
    Likes:
    34,251
    England (south coast)
    It would be helpful to look at the immunology of the patients who are suffering from chronic post Ebola syndrome. But those patients are located in Africa, so not so accessible to western scientists.
     
  3. lansbergen

    lansbergen Senior Member

    Messages:
    2,511
    Likes:
    2,722
    Cleared from the plasma is no garantee it is cleared from tissue .
     
    halcyon likes this.
  4. Jammy88

    Jammy88 Senior Member

    Messages:
    137
    Likes:
    128
    Italy

    That's so demotivating and you're right indeed :(

    Hey, wait… should we all get Ebola?! :D lol… not funny at all, I know, but….. :-|
     
  5. msf

    msf Senior Member

    Messages:
    3,269
    Likes:
    4,563
    I have seen a patient say that having ME was worse than having cancer (I forget which type), but if there is one disease I would never swap ME for, it is Ebola, not unless I had a death wish, and a death wish to die in one of the most painful and frightening ways possible.

    As for the continuing immune activation one month after the virus had been cleared from the plasma, it doesn't seem very surprising, since CD8 T-cells are supposed to last at least that long, if not longer.
     
    Valentijn and Bob like this.
  6. Kati

    Kati Patient in training

    Messages:
    5,466
    Likes:
    19,617
    Sorry for being demmotivating, @Jammy88 i was just speaking of the current reality... Hopefully this will change.

    A smart researcher would compare the blood of Ebola patients with the blood of ME/SEID patients, amd compare what's similar and what's different.

    Nancy Klimas has been successful in getting grants that way
     
    Bob likes this.
  7. halcyon

    halcyon Senior Member

    Messages:
    2,345
    Likes:
    5,491
    If I recall correctly, Ebolavirus sequesters its RNA and forms dsRNA in a way that's similar to enterovirus. It's also able to interfere with cell mediated immune pathways much like enterovirus. It seems conceivable that, assuming the person survives the infection, some amount of virus could persist in the tissue and prolong immune activation.

    It's also interesting that Ampligen has shown some promise for treating Ebola infections.
     
  8. Sidereal

    Sidereal Senior Member

    Messages:
    3,097
    Likes:
    17,195
    It's also interesting that it's one of those viruses causing post-viral fatigue syndrome.
     

See more popular forum discussions.

Share This Page