@perrier
The PEM is horrific. FRom any movement she gets burning, up the spine, hips, legs, elbows, non stop severe pain and burning, plus malaise, sick feeling, nausea.
Burning paresthesia is a symptom of....
Nutritional Neuropathy Clinical Presentation (Updated: Dec 28, 2015) this article also includes some photos to show certain conditions to assist in identification and provides common causes of the deficiency A copy of this article may be helpful to the doctors. Most MDs don't have training in nutrition.
http://emedicine.medscape.com/article/1171558-clinical
"Peripheral neuropathies due to nutritional deficiencies have few individually characteristic signs but can be differentiated by observing other symptoms of the patient's underlying systemic disease.
Neuropathies mostly affect the long fibers first, starting in the feet and progressing upward. Once they have progressed to the calf, symptoms may appear in the hands...
...
Thiamine (vitamin B1) deficiency
Dry beriberi
is characterized by severe burning dysesthesias (feet more than hands),
weakness and wasting (distal more than proximal), trophic changes (shiny skin, hair loss), and acrodistal sensory loss in a graded fashion typical of dying-back polyneuropathies.
Some patients do not become symptomatic, possibly because they are absorbing thiamine produced by bacteria in the large intestine. However, one half become symptomatic by 7 weeks; by 15 weeks, axonal changes start to appear histologically.
The neuropathy begins with fatigue and loss of sensation, pain, and heaviness in the legs. Then, pretibial edema develops, along with glove-and-stocking paresthesias and difficulty with tasks such as climbing stairs and standing on one leg.
If the thiamine deficiency is long standing, muscles on the dorsum of the feet atrophy and paralysis can ensue.
Difficulty with talking or swallowing may also be noted.
...
Pyridoxine (vitamin B 6) deficiency or excess
This deficiency must be suspected any time a sensory polyneuropathy occurs after hyperesthesia-causalgia syndrome.
First, bilateral numbness and tingling begin in the distal feet. This proceeds proximally up the feet and legs, occasionally appearing in the fingers and hands.
Then pain becomes prevalent in these areas, and symptoms can include a burning sensation in the feet.
In rare cases, patients experience loss of power in the legs, in which sensory loss is greater than motor loss; the etiology is axonal loss.
One week after the removal of vitamin B6 from the diet, levels of xanthurenic acid increase and levels of pyridoxine decrease in the urine. At 3 weeks, EEG abnormalities manifest, and tonic-clonic seizures refractory to anticonvulsants may follow.
The 4 main symptoms and signs are as follows:
- Cutaneous mucosal symptoms - Glossitis, conjunctivitis, cheilosis
- CNS symptoms - Lethargy, decreased level of consciousness, anorexia, vomiting, seizures
- Ascending sensory polyneuropathy
- Anemia - Lymphopenia with eosinophilia
Neuropathy due to toxicity occurs 1 month to 3 years after the individual starts excessive consumption.
...
Pantothenic Acid (vitamin B 5) deficiency
This
manifests as painful burning paresthesias in the feet, ataxia, and hyperreflexia, followed by weakness, fatigue, apathy, and psychiatric disturbances 5-8 weeks later...
...
Hypophosphatemia
Invariably found in patients on total parenteral nutrition, this deficiency causes tingling paresthesias in the tongue, fingers, and toes but can progress to severe weakness and areflexia, sensory loss, and cranial neuropathies..."
*****************************************************************************
http://altmedrev.com/publications/7/5/389.pdf
I put 2-3 ml of magnesium into the Myers IV, done 5 times per week. As well as 1 ml of b complex.
It may be helpful to calculate out how much of the vitamins are actually going into the formula since B complex often has quite a different amount of each depending upon who makes it. Whoever suggested putting her on the Myers IV may be able to help decipher this. Also, what forms of the vitamins are being administered and what form of magnesium. How is her diet/drink/medicine regimen?
***Keeping a good time log with what was administered along with the ensuing responses will greatly aid in identifying cause and progression, and further aid in sorting out confusion. If you log it on computer it will be easier to share with doctors, who hopefully will take the time to look at it. It takes a lot of time to log, more than it takes to administer something by far. Is there any chance that your medical will allow a home nurse visitation who is up on recording data in medicalese?
Note that sometimes the body in weakened condition cannot handle large amounts or active forms of vitamins well as they can be too stimulating, despite the need, so having a nurse around to monitor vitals would be helpful. In the U.S. IVs are usually done in doctor's offices.
Other more general descriptors of paresthesia and causes listed briefly here:
paresthesia is a symptom of....
http://www.rightdiagnosis.com/p/paresthesia/intro.htm
) to be able to do it again. I wonder what you were dealing with which resolved with ABX - do you have any ideas?
