hello everyone. i am almost certain methylation is at the core of my health issues. i haven't been able to start methylation therapy as i seem sensitive to the slightest change. i think other things i take might be affecting my response. i would appreciate your help. i feel like i increasingly can't think my way out of a paper bag. here are my questions: 1. both Yasko's and Freddd's protocol say to add the supplements in a specific order. i already take some of the supplements from the later stages. i seem to depend on these for my daily function. do you know a way to gradually move from taking later stage supplements to taking earlier stage supplements *while maintaining basic mental function*? 2. do you know a dr (md) who can help me with this transition over phone / skype? any ideas? Ford details: 1. my organic acids test result implies low b12, low glutathione and low magnesium. b12 improves my allodynia and initially improves mental clarity. magnesium improves my mental clarity. i have been taking more than 400mcg folic acid, but less than 160mcg hb12 for 1-5 years. i have been taking acetaminophen / paracetamol for 5+ years. coffee makes me feel worse after methylation treatment. brown rice (suspected methionine source) eventually makes me feel worse in a similar way to b12. so i suspect all this is due to a methylation issue, especially given my snps (in my signature). 2. 160mcg hydroxo b12 drives my potassium gluconate demand to 2160mg daily. i was unable to tolerate 1/128th of a neurological health formula pill. so i haven't been able to start the Simplified Methylation Protocol. 3. i take the following, amongst other things. i am fairly sure i depend on them for daily function. berocca (b vitamin drink with 400mcg folic acid and many somewhat high b vit doses) 1/8th centrum advance multivitamin pill (contains 50mcg folic acid) d-ribose 6g co-enzyme q10 200mg acetyl l carnitine 1000mg alpha lipoic acid 600mg 4. i am searching on mthfrsupport.com for a dr. the closest i have found is Dr Enlander, but his methylation focus seems to be on ensuring methylation supplements are taken. i am not sure he can help me move from my current supplements to the Simplified Methylation / Active B12 Protocol ones.