To my understanding, glutathione is consumed when the body is under severe stress from either physical or mental trauma. After going through two surgeries in the past two years and severe mental/physical trauma, it seems like my body has depleted glutathione reserve. So it seems like my methylation cycle is blocked from depleted glutathione, which has led to gut problems, more adrenal issue, and mitochondrial dysfunction. Also, antibiotics that were given after each surgery tanked the gut health, further depleting glutathione resulting in a vicious cycle. So one protocol I came up with was to supplement with reduced glutathione that contains precursors of glutathione, which are glutamate, glycine, and cysteine. Unfortunately, I have become more and more sensitive to thiol (sulfur) and every time I take cysteine, my body would flare up and start itching everywhere. It looks like I am trapped in this vicious cycle! Is there any other ways to increase gluathione level in the body without taking supplements that contain thiol? (ALA, cysteine, p5p, MSM, taurine, B6, NAC, etc) ps: I am still reading Freddd's stance on glutathione level. If you have had negative reactions to gluathione, please share it with me. Thanks.