Hello friends. I have looked at my 23andme test and found I have a mutation on CBS A360A (++, uh oh), however, on the other two CBS genes, I am -/-. I have read the heartfixer guy's website, but he just calls CBS gene overall, but doesn't talk about specific SNP's. How do you know which one means something, or is it even if you have +/+, you are still in trouble, or you need all 3, or how does that work? I'm pretty sure I have a problem with it anyway.. about a year ago when I was at my worst and knew nothing about all this methylation stuff, I pinpointed non organic produce was a problem for me because it literally made my arm go numb and I got weird eye twtiches from eating it. I then researched a ton into it and found out it was because I was sensitive to the sulfites/sulfates in the chemicals they spray on the produce, but now this explains the reason why, I had no idea before. Anyway, besides CBS, what about the other genes like MTHFR, do you only need one or two to have a problem, or you need all them to have a problem? Okay thanks guys, looking forward to contributing and learning more from this forum.