I post this in light of Dr Naviaux's promising pilot suramin trial in autistic children, and the suggestion that the drug may benefit ME/CFS patients as well. Dr Naviaux hypothesizes that a CDR (cell danger response) mediates both diseases, and that by correcting it, a switch to healing will be flipped. So my question is how similar is autism to ME/CFS? I don't know much about autism and its underlying pathology and I'd be interested to learn more. Obviously these are very different diseases from a symptomatic standpoint. For one, people with autism don't have PEM. There do seem to be some symptomatic similarities such as sensitivity to noise and light, and increased difficulty with social interactions. Furthermore Dr Naviaux has identified metabolomic similarities between the two diseases, and Dr Yasko has researched common MTHFR mutations. Is there anyone with greater knowledge in this area who might be able to shed some light on the subject?