ME/CFS: A disease at war with itself
We can all agree that ME/CFS is a nasty disease, particularly in its severe form, but there are abundant nasty diseases in the world. What is unique and particularly confounding about our disease is that so much controversy surrounds it, and not only surrounds it, but invades it too.
Discuss the article on the Forums.

How Long Should we Methylate For?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by Uno, Feb 21, 2014.

  1. Uno

    Uno Senior Member

    Messages:
    123
    Likes:
    39
    Brighton, United Kingdom
    Hi folks

    I haven't posted in a while - but it's been a long time since I started methylation and I wondered how long exactly are we supposed to stay on it for and if we do stay on it indefinitely, is it dangerous or harmful in any way?

    I can't live without my B12 - when I don't take it I feel awful. I haven't taken any MTHFR tests to determine which mutation I actually have but I plan on doing so when I get some money.
     
  2. shah78

    shah78 Senior Member

    Messages:
    160
    Likes:
    102
    st pete , florida
    Myhill clams she sees people able to discontinue methylation once it gets started. I can't imagine doing so if you have the genetic defects, so many of us have. If you just have a b12 deficiancy and get the" tank" filled up, then maybe this is what she is talking about. Like you, my life without my b12/folate how be a calamity.
     
  3. PeterPositive

    PeterPositive Senior Member

    Messages:
    847
    Likes:
    442
    Good question, have been taking supplements for almost 2 years an my homocysteine is still elevated ... recently did the genetic test and found out the mthfr c677t mutation, so now I am taking extra b12 and mehtylfolate. In my blood tests they are both elevated but my methylation is still running slow...

    I guess most people here would have elevate serum folate and B12 given the dosages I have seen posted. I am nowhere near the 5-10mg (and higher) that some of the people here take on a daily basis. I can handle 2mg max, for now.

    I would agree with shah78, if there are genetic defects those bottles of supplements are for life :)
     
    Last edited: Feb 22, 2014
  4. Critterina

    Critterina Senior Member

    Messages:
    899
    Likes:
    437
    Arizona, USA
    Peter,

    Congratulations on becoming a senior member!
    I was just thinking about your homocysteine being high even after 2 years of methylation. Did you also have the BHMT 08 SNP? TMG may help if you do.
     
  5. Soundthealarm21

    Soundthealarm21 Senior Member

    Messages:
    355
    Likes:
    494
    Dallas, TX

    These are vitamins that are necessary for proper body functioning. You can take these for the rest of your life. It's especially important to take them if you have genetic defects or don't get enough of them in your diet.
     
  6. PeterPositive

    PeterPositive Senior Member

    Messages:
    847
    Likes:
    442
    Oh, I didn't notice that. So do I win anything? A bit of health would be cool :)

    I am heterozygous for BHMT 04, while the others are fine. I have tried TMG but it is too tough on my digestion.
    One of the possible problems is that I have used supplements with folic acid for most of the time and recently I discovered that I am MTHFR C677T +/+, so have switched to methylfolate.

    thanks
     
    Last edited: Feb 22, 2014
    Critterina likes this.
  7. adreno

    adreno on the beach

    Messages:
    3,026
    Likes:
    2,913
    Europe
    Perhaps you will be able to reduce to a lower maintenance dose when your symptoms are under control, but I think you will always have to support your methylation with supplements.
     
  8. Soundthealarm21

    Soundthealarm21 Senior Member

    Messages:
    355
    Likes:
    494
    Dallas, TX

    Lol I just realized I've become a senior member since the last time I logged on. How do you become one?

    Yes I'd like some health with my new status symbol ;)
     
    Critterina likes this.
  9. PeterPositive

    PeterPositive Senior Member

    Messages:
    847
    Likes:
    442
    I guess it's due to the post count.
    Cheers
     
  10. Uno

    Uno Senior Member

    Messages:
    123
    Likes:
    39
    Brighton, United Kingdom
    Thanks everyone. When I take further tests I will probably post the results on here!
     
  11. Critterina

    Critterina Senior Member

    Messages:
    899
    Likes:
    437
    Arizona, USA
    It looks like 100 posts = Senior Member. When that happened to me I thought "Oh, I'm dangerous now!" :p
     
    Soundthealarm21 likes this.

See more popular forum discussions.

Share This Page