When methylation increases after having been sluggish I've found it is fairly common to feel worse for awhile. This would make perfect sense as undesirable substances, that should have been more effectively cycled out of the body, have accumulated and there is now a larger then normal quantity of trash that needs to be dealt with. It would make sense that given enough time this backlog would sort itself out, but any impediment to its removal is going to make the experience last longer then necessary. This got me thinking...Can anyone clarify how your body actually rids itself of this garbage once methylation picks up? Is it mostly through urine or the bowels? Could you actually improve the speed up the elimination of the backlog of trash by increasing your fluid intake or the frequency of your bowel movements?