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How does fish oil cause fever?

Ocean

Senior Member
Messages
1,178
Location
U.S.
I tried Krill oil today and my temp is up to 100.7 soon after. Normally it's about 99.3 to 99.5. It does go above 100 but usually that only happens at night and. I did a search on fish oil and fevers and several sites say stop taking fish oil if you get a fever so it obviously isn't something unheard of. I'm just wondering how fish oil could cause a fever, what mechanism is causing it? I have no problem eating fish or other seafood. I'll probably try it once more at some point before assuming it's related to the krill oil. Thanks.
 

Ocean

Senior Member
Messages
1,178
Location
U.S.
Not sure of the quality, it's Now brand, which has worked fine for me with other supplements. So fish oil can cause an immune response, that's interesting.
 

alex3619

Senior Member
Messages
13,810
Location
Logan, Queensland, Australia
It is very unlikely, but not impossible, for fish oil to cause fever unless its from contaminants. However, fish oil stimulates series 3 eicosonoids while suppressing series 2 eiconsanoids. Series 3 are usually less inflammatory. In some individuals the inflammatory series 3 eiconosanoids might be a problem.

The other issue is this. Fish oil suppresses the series 2 eicosanoids. If you have an infection, you have a fever. The series two eicosanoids can increase inflammation and hence the immune response. If you keep taking the fish oil you keep suppressing your immune response, leading to a worse infection, leading to a worse fever. The fever is not from the fish oil however, but a response to infection in this case. The fish oil just limits your ability to fight the infection.

Bye, Alex
 

Enid

Senior Member
Messages
3,309
Location
UK
Interesting thread - I've had to drop supplementary fish oils and restrict my oily fish intake to twice a week only. Can't understand why but too much makes me want to vomit now.
 

Ocean

Senior Member
Messages
1,178
Location
U.S.
Thanks for the ideas. I've been eating a good amount of fish so I may just stick with that for now. I think the fever may have been coincidental but since I ended up getting insomnia from the fish oil, as I seem to do with anything that has an effect of giving energy or mental clarity, I'm not going to take it again for now. I may try later with a liquid, that way I can control the dosage.