Hi everyone,
My husband has MTHFR 1298 +/- and MAO A -/-. I take this to mean that he has less ability to transform tryptophan into 5-htp leading to less serotonin, and he has a high ability to degrade serotonin, so he has always had some trouble with depression and also now he responds well to 5-htp supplements without mood swings. My DIL has MAO A +/- and she doesn't have MTHFR 1298 and she has some mood swings.
I would like to gather more information about this if any of you want to contribute then please post your MTHFR 1298 and MAO A mutation status and also your average tendency to depression on a scale of 0 - 10 and your tendency to mood swings on a 0 - 10 scale, meaning mood swings within a single day. All information is useful, even if you are 0 scale on mood swing and depression. Also put down mood swings with 5-htp if you have tried it. You can add any relevant comments if you wish. Also you could comment on your response to depression medications if you have ever taken any and wish to share that information.
For an example I would rate my husband like this:
MTHFR 1298 +/-, MAO A -/-, Depression 2.5, Mood swings 0, Mood swings with 5-htp 0
Thanks!
Kimsie
My husband has MTHFR 1298 +/- and MAO A -/-. I take this to mean that he has less ability to transform tryptophan into 5-htp leading to less serotonin, and he has a high ability to degrade serotonin, so he has always had some trouble with depression and also now he responds well to 5-htp supplements without mood swings. My DIL has MAO A +/- and she doesn't have MTHFR 1298 and she has some mood swings.
I would like to gather more information about this if any of you want to contribute then please post your MTHFR 1298 and MAO A mutation status and also your average tendency to depression on a scale of 0 - 10 and your tendency to mood swings on a 0 - 10 scale, meaning mood swings within a single day. All information is useful, even if you are 0 scale on mood swing and depression. Also put down mood swings with 5-htp if you have tried it. You can add any relevant comments if you wish. Also you could comment on your response to depression medications if you have ever taken any and wish to share that information.
For an example I would rate my husband like this:
MTHFR 1298 +/-, MAO A -/-, Depression 2.5, Mood swings 0, Mood swings with 5-htp 0
Thanks!
Kimsie