I think a few ways have been identified--leucine, ketamine....? I am experimenting with hefty doses of BCAAs (containing leucine) and while it is not preventing fatigue or increasing endurance, it does seem to largely prevent PEM. What other ways are their to stimulate mTOR? And if I have the terminology wrong, please correct me! This seems like something that we might be able to safely experiment with until research tells us more--reducing the mTOR inhibitors and increasing things that stimulate it.