I have two points with this topic: 1)I discovery during my CFS joruney that hot showers triggers fatigue, i begin to wonder why. I saw some comments that people also experienced that and solved their problems with DHEA and Pregnenolone. I begin to think aswell about thyroid not functioning well, since the thyroid controls temperature. So i started taking Selenium, Tyrosine and lugol to support thyroid. For now i didn't notice any difference. I wonder if acne, white coated tongue, intolerance to hot showers and fatigue related root causes. Does anyone experimented the same thing? 2)For what i saw, there are many kinds of fatigue, for instance: physical fatigue, which people would benefit with d-ribose, ozone, creatine COQ10. It's not my case, because i can exercise normally very very hard without feeling tired. The source of my fatigue is different, and not lack of ATP, so things that optimize cellular function are useless to me. I don't even know how to identify the source of my fatigue. I'm thinking of giving a shot to pregnenolone and DHEA. Does anyone have a tip to identify the source of my fatigue? I'm glad i discarded ATP production.