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Hornig/Lipkin cytokine study out now - press release

Discussion in 'Latest ME/CFS Research' started by Sasha, Feb 27, 2015.

  1. Scarecrow

    Scarecrow Revolting Peasant

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    That's just it - the sample size is far too small to draw a conclusion. 4 of the 29 patients had duration 3 years of less, and 3 2 of those patients did not respond, one had a reaction to treatment and did not continue. It takes just one of them to be a responder to almost balance the period of illness duration and then you wouldn't even be thinking about a trend.
     
    Last edited: Aug 23, 2015
    MeSci and SOC like this.
  2. Scarecrow

    Scarecrow Revolting Peasant

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    They're just simple means based on 18 responders, 10 non responders and one did not complete. Note that I've recalculated because I did not notice that one of the 4 short duration patients had withdrawn.
     
  3. msf

    msf Senior Member

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    Yes, I agree, the trend might not be significant.
     
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  4. BurnA

    BurnA Senior Member

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    In a cohort of 30 patients one or two long durations in either category can easily skew the averages. I dont think averages provide any useful data. In fact i would say they should almost be ignored unless dealing with very large sets.
     
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  5. BurnA

    BurnA Senior Member

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    Just curious, would rtx patients who relapse have similar biological profile to those of short duration or long duration ? In other words would the response reset the system or not ?
    Has this been looked at ?
     

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