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Nitric oxide and its possible implication in ME/CFS (Part 2 of 2)
Andrew Gladman explores the current and historic hypotheses relating to nitric oxide problems in ME/CFS. This second article in a 2-Part series puts nitric oxide under the microscope and explores what it is, what it does and why it is so frequently discussed in the world of ME/CFS....
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Holotranscobalamin is only 10-30%...

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by PeterPositive, Aug 23, 2014.

  1. PeterPositive

    PeterPositive Senior Member

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    Just found this simple graph showing the small slice of B12 that is really biologically active versus the rest floating in the serum and unusable.

    [​IMG]
    Source

    Interesting, isn't it?

    If we add partial methylation blocks, transport and conversion issues etc... I can see why people here (myself included) need B12 by the bucketload to get going.
    Little Bluestem, ahmo and Helen like this.
  2. misskatniss

    misskatniss

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    Germany
    Yeah, and why a normal B12 level in the blood says NOTHING about the bioavailable amount! And no doc told me that which is even worse.
    PeterPositive, ahmo and Sushi like this.
  3. PeterPositive

    PeterPositive Senior Member

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    Indeed that's pretty telling of the relevance of serum B12 values... :rolleyes:
    PennyIA likes this.

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