Here's an article. http://alisonvickery.com.au/what-if-this-was-about-the-liver/ For the facts. I'm on cutler chelation, plus some of shades stuff. I took too much huperzine (an AchE inhibitor) for too many weeks and probably also aggravated SIBO, so now I'm getting this really pronounced surge in histamine sensitivity I've not experienced in years. Don't seem to benefit much from directly treating MTHFR, but I suspect perhaps some CBS issues. But like many, I am skeptical of CBS. But I still have sulfide and thiol issues, and now with the histamine thing I am really, really having a hard time tolerating meat. And plus I can't afford the good stuff and don't have a 'hook up' with any legit farmers or hunters. So my diet is a wreck. I mean frankly, I've been trying to avoid the crazy raw vegan diet for about 4.5 years. But, due to all these really weird curve balls I'm sort of getting pushed away from Weston Price into just plant based diet. And some people speculate that, like with GAPS and SCD, the brown rice and organic corn I eat might be feeding more unfavorable gut flora which promote more histamine and other systemic conditions that increase chronic fatigue and make doing chelation challenging. And really its diet that has stumped me for 4 years of not being able to chelate properly. I then saw, that there's a connection between methylation and histamine. So maybe CBS makes histamine worse? In which case again, I lose on meat. And recently, I read pretty good arguments against saturated animal fats, specifically arachidonic acid, promoting histamine issues. . .Denise Menger's blog certainly put out some tough arguments. Maybe some people are sensitive to AA because of some underlying SNP. And meat stock is REALLY bad. Like evidently that just cooks up tons of histamine. I realize I haven't tolerated heavy stocks well, well ever. Frozen salmon didn't take to me well. Regular factory farmed meat is the worst, as it's been sitting around for some time on the shelf. I wonder what caffeine does to histamine. . . " Step 3 – High Protein, Nutrient Rich, Anti-Inflammatory Diet It is simply not necessary to do a “detox.” What is necessary is a nutritious diet. A poor diet will compromise the liver, whilst a high protein, nutrient rich diet, will give the liver all the ingredients it needs to detoxify itself. Simplistically, any toxins need to be avoided. Phase 1 needs anti-oxidant and glutathione rich nutrition. Phase 2 need protein, glutathione, and a sulfur rich diet. Step 4 – Rebuilding Phase 1 I developed a bio-individual diet where my body stopped hyper-responding. Essentially it was organic, low in histamines, and paleo-ish. Once my body had stopped hyper-responding I started to work on manipulating my diet to include more phase 1 supportive foods. This has included in particular un-denatured whey protein, herbs and micro-sprouts (particularly broccoli sprouts), cruciferous vegetables, and citrus (other than grapefruit) which I tolerate." Now If you know Cutler, you know there's a lot of problems with this particular diet she is pointing out. When you cut out thiol foods and sulfur foods and sulfides (CBS diet). . .and now grains...legumes.. . meat....WTF do I eat? I mean, I denied that I had a thiol issue for a year, because frankly, I feel more 'stable' just eating queso every day. But I mean I spent 2014 completely wrecked, and not chelating. The only diet I ever thrived on and lost weight on and healed on. . .was like a low fat, low carb, pesco-vegetarian version of Weston Price. . It was a harsh diet, but it gave me 3 years of life in what has otherwise been persistent illness since the 7th grade. . .