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High Prolactin Causes Severe Fatigue.

Discussion in 'Hormones' started by Ema, Jul 7, 2013.

  1. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    Yeah I have high e2, but not super high. I know I need to lower it if I want to have a sex drive ever again lol Even, I discovered that high e2 and low free test are probably involved in my CPPS. But I think that working in the bigger picture will eventually bring my shitty hormones to good levels.
  2. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    I dont know if its a cfs thing or not but even on trt and arimidex I cant get my freeT into the upper third of the range. Its only just in the normal range which is an improvement but have thought about bromocriptine to raise dopamine and lower prolactin?
    Hormones can be a tricky thing to balance out??
    Beyond likes this.
  3. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    I am highly interested in the mechanism that blocks our free test conversion. Somehow I am inclined to say it has to do with chronic inflammation and HPA shittyness.
    heapsreal likes this.
  4. Ema

    Ema Senior Member

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    More on prolactin and the immune system can be found here:

    http://rphr.endojournals.org/cgi/content/full/57/1/435

    So it may be that prolactin helps protect against high levels of IL-6? It is all very interesting to me.
  5. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    Maybe the body produces high prolactin and E2 to counter inflammation.
  6. heapsreal

    heapsreal iherb 10% discount code OPA989,

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    There seems to be this big circle how it starts got know idea but insulin resistence is involved then we put weight on which cause increase inflammation and body fat has an enzyme that converts testosterone to E2, high E2 make it hard to lose weight, then we start looking at things like prolactin and sex hormone binding globulin, we turn into a hormonal mess.

    Many hormonal and inflammatory things can improve with losing weight but we have so many things against us even with say a low carb diet. Metformin is a med that can improve insulin sensitivity and aid in losing weight and with the addition of bromocriptine maybe further increase insulin sensitivity. Arimidex can lower E2 and can also aid in losing weight but as weight comes down we produce less E2 so we have to be careful not to lower E2 too much, so its a med that we may only need for a certain length of time. Im not sure about this but maybe low dose T3 could also help with weight loss. Once we have weight down to a good level many of the meds wont be needed as insulin sensitivity improves with weight loss?? Exercise is really good but with cfs we are backed up against the wall with this.

    The above is just a theory, trying to break the cycle of these different mechanisms holding us back in losing weight.
    With cfs we tend to have 2 types of body types fatties and skinnies. Im a dam fatty, finding it harder and harder to lose weight.:bang-head:
  7. Beyond

    Beyond 10% of discount in iHerb!--> PEZ915

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    I am a skinny so the theory above does not fit for me. Interesting for you, I knew being fat makes men more estrogenic.

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