Hi, Question, should all disease be affected by the same issue, high Glutamate? While i become more and more sick i have got RLS ( low dopamin , high Glutamate) , it looks like im AHDH at the moment ( High Glutamate low Dopamin), and my symptoms look more and more on parkinson ( High Glutamate low Dopamin), and dementie ( high glutamate and maybe low Dopamin?) .. I read a good articel about ADHD and there they say that ADHD meidicine have something that stopped glutamata and become a very good treatment. http://www.corepsych.com/2010/11/adhd-and-glutamate-neurotransmitters/ Maybe its also a good supplement for us? And that combinated with maybe some B3/NADH for boosting dopamin ? Because of methylation problems you cant make good dopamin right? Would that be the issue that glutamate raise? I react good to taurine ( only ive got a CBS homozygous problem). Would that be because that lowers glutamate and higer GABA? I find a good post also at phoenix rishing about Glutamate/glutamine and the role Of B3. http://forums.phoenixrising.me/index.php?threads/how-to-lower-glutamate-pharmacologics.23648/ NADH/ B3 plays also a role in alzheimer huntington and parkinson... And we have all low glutamine but high glutamate its al because of the convertion that doesnt work well? Is the problem all bad methylation? Because bad methylation affect dopamin support( neurotransmitter support ). What do you guys think? In our country we also have a site of ME/CFS. And there you can read also that much ME patients also have ADHD or ADD. ( because of low dopamin and high glutamate). So there has to be a connection!