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A Little Poisoning Along the Road to ME/CFS
Looking at my symptoms, many of which are far less these days and some are gone, it would be easy to figure that I'd just been dealing with some heavy-duty menopausal issues.
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High Dose Selenium Significantly Improves My Fatigue and Brain Fog

Discussion in 'General Treatment' started by Hip, Jan 5, 2014.

  1. mabelark

    mabelark

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    Thank you, Hip. I will give the Methyl L-Selenocysteine form a try. I am looking forward to it arriving. Will try to find my selenomethionine tolerence level in the mean time, starting with 300 mcg.
     
  2. end

    end Senior Member

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    Is there a general consensus on which form to take???

    @Hip has linked on another thread to this study: http://www.ncbi.nlm.nih.gov/m/pubmed/11878751/

    Which outlines SelenITE is the effective form for anticoxsackie b5 activity. They further outline that the Selenate and Selenomethionine were not effective at all!

    "We studied the antiviral effects of three selenium compounds on Coxsackie virus B5 replication: five microM selenite reduced viral replication, whilst 10 microM selenate and selenomethionine did not exhibit any antiviral activity."

    An organic mineral is always better in my book. But given this study, I am not sure which to buy
     
  3. brenda

    brenda Senior Member

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  4. Hip

    Hip Senior Member

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    If you know you had coxsackievirus B5, certainly the sodium selenITE form of selenium would be good to try.

    However, any form of selenium has potent antiviral effects against enteroviruses: if you look at the links to studies provided in the first post of this thread, you will see many studies which show selenium deficiency causes significantly increased virulence of coxsackievirus B3.

    So I think the main antiviral benefits of taking selenium result from obliterating any selenium deficiency in the body, thus ensuring your body effectively fights these coxsackieviruses.
     
    NK17 and end like this.
  5. NK17

    NK17 Senior Member

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    This is very interesting, the antiviral properties of selenium!

    I've been taking Solgar selenomethionine with zinc for some months now.

    I was taking the selonomethionine for better thyroid function and the zinc to help heal the gut lining and boost the immune system, all this while on a GFCF diet.

    Since I've high IgG to some of the coxsackieviruses (have to check if the b5 included) I guess I should stick to this?
     
  6. Ninan

    Ninan Senior Member

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    I'm on it! First day with 400 mcg today.
     
    Hip likes this.
  7. outdamnspot

    outdamnspot

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    I wish I could tolerate Selenium -- it was good for energy -- but I felt quite aggravated on it. It seemed almost noradrenergic.
     
  8. adreno

    adreno 3% neanderthal

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    Right, me too. It probably is noradrenergic through increased thyroid function. RS (months ago) seriously kickstarted my thyroid function, and at the moment I don't tolerate anything that increases it any further.
     
  9. outdamnspot

    outdamnspot

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    Interesting. I didn't know that increased function was a benefit of the starch .. though I did find that it generally seemed to amplify a lot of other things I was trying.

    Are you still taking the starch? I just posted another thread asking about Sodium Butyrate, because the starch was dropping my blood sugar too low.
     
  10. adreno

    adreno 3% neanderthal

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    No, but I'm experimenting with other fibers. Butyrate might have some adverse effects in high (supplemental) doses, YMMV.
     
  11. Ninan

    Ninan Senior Member

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    I never tried selenium before. I took 400 mcg (and the 50 in my multivitamin) 4-5 hours ago and I seem to have more energy than yesterday. Kind of wired. Guess it could just be a coincidence.
     
  12. Ninan

    Ninan Senior Member

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    Nope, it was something else. Hard to tell what is what sometimes.
     
  13. TigerLilea

    TigerLilea Senior Member

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    I'm glad that someone pointed this out. Wikipedia is a very poor source for accurate information, especially when it concerns people's health. PubMed or the NIH are much more reliable sources for accurate and safe information. :thumbsup:
     
    adreno likes this.
  14. Hip

    Hip Senior Member

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    Are you able to provide reliable source for your statement that Wikipedia is a very poor source. ;-)
     
  15. knackers323

    knackers323 Senior Member

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    I am noticing a pretty big improvement a few hours after taking big doses of selenium. 700mcg.

    It seems to be the more the better. I'm aware of the toxicity concerns.

    I wonder why this is helping?
     
  16. end

    end Senior Member

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    I guess that's one of those "million dollar questions" :)

    I remember reading along the lines of - Selenium coating implanted devices have been shown to completely inhibit biofilm formation. Se also plays a role in GSH production and function. And like @Hip has pointed out on this or another similar thread Se also plays a role in limiting Coxackie B infections. I think Se has multifaceted benefits like many natural compounds out there
     
  17. Tunguska

    Tunguska

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    Works for rats: http://www.ncbi.nlm.nih.gov/pubmed/9307047

     
  18. Hip

    Hip Senior Member

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    I imagine this immediate benefit you are feeling will be something along the lines of the dopaminergic boost that @Tunguska posted above.

    In my case, I get no immediate benefits from selenium, but after around 10 days taking it, my ME/CFS is noticeably improved.
     
  19. Jarod

    Jarod Senior Member

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    FYI:

    search yahoo.....: "selenium overdose"


    http://www.easy-immune-health.com/selenium-overdose.html

    http://aids.emedtv.com/selenium/selenium-overdose.html
     
    end likes this.
  20. end

    end Senior Member

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