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High dose of vitamin C, any experience?

Discussion in 'General Treatment' started by JuliaMaple, Aug 18, 2017.

  1. JuliaMaple

    JuliaMaple

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    Hey there everyone,
    For various reasons I consider trying high dosis of vitamin C. Some of them being inflammation in my body, chronic swollen lymph nodes without a clear reason, adrenal problems (low aldosterone).
    And so much more, too much to name.

    I was wondering about experiences of others, if you tried:
    How much did you take? Which type? What did it do for you?
    And are there any risks I should be aware of?

    I have 250mg tables, and want to take 2 (so 500mg) every 30 minutes, until my bowels react to it. Then I stop and use that dose (slightly less) the next day.
    I have ascorbic acid, which is probably not the best right? What would be better?

    Loads of thanks in advance :)

    (Edit:
    Diagnosed with POTS and low aldosterone.
    Chronic fatigue since I was 16, (33 now) Often have hypotension and low heart rate/bradycardie, but no adrenal insufficiency. It started after having Epstein Barr/cytomegaly virus.
    Medication: Only fludrocortisone)
     
    Last edited: Aug 18, 2017
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  2. David Jackson

    David Jackson Senior Member

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    Hi Julia,

    I say go for it; see what you can get up to.

    I take 5ml of ascorbic acid, 4 times a day, and think I could get away with much more However, even from this amount I saw an improvement.

    Check out Andrew Saul on YouTube for info on Vitamin C megadosing :)
     
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  3. Research 1st

    Research 1st Severe ME, POTS & MCAS.

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    I would check your blood Vitamin C levels first before taking masses of Vitamin C. If you have low Vitamin C it will help, if not, you just pee it out and waste your money. Hopefully it will help you by giving you stronger immunity to common colds etc.
     
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  4. Tammy

    Tammy Senior Member

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    It's an individual choice but I would consider Ester C without a lot of other addiditives.
     
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  5. JES

    JES Senior Member

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    Ascorbic acid may be too acidic for your stomach, and it has the bowel tolerance issue. A better form would be liposomal vitamin C, which in my experience has neither of these side effects. Vitamin C plasma levels have been found to correlate inversely with EBV antibody levels (source), so it makes sense to trial Vitamin C if you suspect EBV.
     
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  6. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    I know how great it feels to take a lot of Vitamin C. One time long ago in the middle of a cold or flu I took 22gm of Vitamin C before I ever developed diarrhea. My cold/flu symptoms felt much better. I don't recall how long I persisted in taking Vitamin C, and most of the time I took mineral ascorbates (Vitamin C bound to magnesium, calcium, zinc). Eventually I developed stress fractures in my feet. The radiologist could not explain why this was happening. He asked, "What have you been doing to your feet?" I wasn't bedbound at the time, and prior to developing the stress fractures, I was able to walk 20-30 minutes per day.

    Be careful with taking excessive amounts of Vitamin C. It may be OK for the short term, but long term it will pull minerals from your body. I think I developed stress fractures due to excessive intake of Vitamin C. My bones had become depleted of minerals. Some time later when I saw a naturopath she told me to not take more than 2000mg of Vitamin C per day.

    http://www.acu-cell.com/vitc.html#overdose
    http://www.acu-cell.com/vitc.html#copper
    Here are some examples of mineral ascorbate products:
    https://www.amazon.com/Roex-Vitamin-Mineral-Ascorbates-Tablets/dp/B006UNUTNO
    http://www.integratedhealth.com/supplements/vitamin-c-products/buffered-c-powder-8-oz.html
     
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  7. Learner1

    Learner1 Professional Patient

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    This is utter nonsense. I had high dose IV vitamin C (50-75g) to treat my stage 3 uterine cancer. I am now cancer free...

    https://www.cancer.gov/about-cancer/treatment/cam/hp/vitamin-c-pdq

    Mark Levine at NIH found there is bowel tolerance but IVC brings blood levels up higher than oral.

    https://irp.nih.gov/pi/mark-levine

    As for CFS:

    https://www.google.com/url?q=http:/...ggPMAE&usg=AFQjCNHkmgTE8U003TO00kqwfoAF3YBlsA

    For infections:

    https://www.ncbi.nlm.nih.gov/pubmed/10543583

    https://riordanclinic.org/2014/02/h...s-a-successful-treatment-of-viral-infections/
     
  8. pamojja

    pamojja Senior Member

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  9. IThinkImTurningJapanese

    IThinkImTurningJapanese Moderator

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    What do you consider a high dose?
     
  10. JES

    JES Senior Member

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    :
    The Linus Pauling recommendation of 6-18 mg was not established scientifically. Linus Pauling Institute now recommends "only" 400 mg:
    In order to get higher plasma levels of vitamin C than from 400 mg, the only way would be to use IV (significantly higher) or liposomal vitamin C (somewhat higher).
     
    Last edited: Aug 19, 2017
  11. pamojja

    pamojja Senior Member

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    In the OP said 1g every waking hour, spread out in half-hourly doses.
     
  12. pamojja

    pamojja Senior Member

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    If one looks at the actual science and the context, one finds that low dose recommended by LPI has rather to do with financial considerations: https://firstlaw.wordpress.com/2012/12/12/oops-they-got-it-wrong/

    Only if you follow the standard assessment by giving up to 2.5 g of vitamin C while testing serum levels. And arrive at serum levels of higher intakes via extrapolation only. Any study testing levels, finds these generally accepted speculations not true:

     
    Last edited by a moderator: Aug 24, 2017
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  13. IThinkImTurningJapanese

    IThinkImTurningJapanese Moderator

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    Now that would be a high dose, and one that would be difficult to maintain.

    I have taken buffered Vitamin C at those doses and been surprised by rapidly reducing cold symptoms. Within a few hours.

    I couldn't sustain such consumption though, it's expensive.

    I take 2 grams daily, probably only 2/3 what I need, but I take it every day. ;)
     
    Last edited: Aug 19, 2017
  14. pamojja

    pamojja Senior Member

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    Actually my 23 g/d being the highest dose of any supplement I take, it is also the cheapest one. Widely available here in supermarkets for 1.95€ per 100g bottle. Even cheaper if one orders wholesale online. At such high doses for many years I wouldn't take pills or capsules, since they all come with fillers/binders I wouldn't want at such high doses.
     
  15. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    Vitamin C can interfere with other lab tests besides glycohemoglobin (HbA1C).

    Influence of Vitamin C on Urine Dipstick Test Results
    http://www.annclinlabsci.org/content/45/4/391.long
    Influence of Large Doses of Ascorbic Acid on Laboratory Test Results
    http://clinchem.aaccjnls.org/content/clinchem/24/1/54.full.pdf
     
  16. IThinkImTurningJapanese

    IThinkImTurningJapanese Moderator

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    Have you noticed a significant difference in benefit from that dose vs. 2 or 3 grams a day?
     
  17. pamojja

    pamojja Senior Member

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    Already linked to posts which would answer that question. Short answer is not comparable.

     
  18. outdamnspot

    outdamnspot Senior Member

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    Does anyone know if Vit C can cause a 'detox' reaction? I take 2-3g of time-release to help me sleep; I noticed a reaction yesterday that resembled the herxes I get on certain herbs (intense apathy, brain fog, depression, GI upset). Last night I upped the dose to 5g and today I feel flu-like with a raging headache etc.
     
  19. pamojja

    pamojja Senior Member

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    I never experienced detox reactions with very high doses. GI upset are usually is a sign you're getting close to bowel tolerance, which also can change a lot over time. Dr. Levy though, talks a lot about it's detox properties, for example here:
     
  20. outdamnspot

    outdamnspot Senior Member

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    I am aware of bowel tolerance -- though my symptoms aren't restricted to the stomach, which is why I thought something else might be going on. I do know, though, that the concept of 'die-off', 'detox' etc. is a bit contested, so hence wasn't sure.
     

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