Hi, I am now quite sure about this because I've tried it on and off many times, and each time I go on the "plan" I can sleep till 7-8am (going to bed 10-11pm). Otherwise I will wake up at 3-4am. Essentially I consume a lot of circumin/curcumin, in the form of turmeric and a supplement called Enhansa (supposedly highly absorbable curcumin). I cook with turmeric in oily food, and consume this for my 3 main meals. I put in about 3tsp of turmeric (15g say) into one large batch which lasts me about 1-1.5 days worth of meals. On top of that, I have one 600mg tablet of Enhansa with my morning meal and two with my evening meal (fat helps absorption of curcumin). Curcumin reduces inflammation in the brain. But it has so many other positive effects it's hard to say which one is doing the job. All I know is it works. If I half the dose the effect wears off, it really is important for me to go to high doses. When I first tried it, I went to very high doses just to see if I could get an effect.