There are a number of people following @Freddd 's protocol. There are also a number of people following its description and belief of paradoxical folate deffeciency. To put it simply, that means if someone experiences folate deffeciency symptoms when it is already receiving methylfolate needs to recognize these symptoms and rise the dosage of methylfolate. A person needs to keep increasing this dosage until his body reaches an equilibrium. That dosage will be the perfect for him and he might be able to lower the dosage later as the body is healing. By increasing the methylfolate dosage each time, someone is experiencing folate deffeciency symptoms (instead of stopping the methylfolate usage) is pushing the body to enter different layers of healing that are described by different group of symptoms as they were written down and grouped by Freddd. So in other words when someone is experiencing these symptoms when taking methylfolate he should consider not stopping the supplement or lower the dosage but increase it instead so it will give the chance to his body to get out of the deffeciency and move to a different layer of healing. This process maybe repeated,a number of times until someone reaches the perfect dosage for him. There are people that are finding adaquate dosage between 1mg to 20mg of methylfolate so there is quite a WIDE spread between different group of people. I am asking people that have found that this description and method of getting out of the folate deffeciency, works for their body to contact me in order to discuss these experiences, as there are not many people that support this approach (or they are scared to follow it), at least that I know of. However there are people that are trying this and would be very interesting to know what is the perfect dosage for each one of them. Also I would like to know if when they found the adaquate dosage for them, where able to reduce it after the body has achieved healing at the deepest layer.