Anyone else have this? My 24 hour cortisol is high. I thought most people with CFS?ME struggled with low cortisol? The lab test definitely makes sense because I have symptoms of high cortisol so I am very glad to finally see a lab test reflecting my symptoms for a change. I wonder if taking steroid nasal sprays over a long period might have anything to do with the high cortisol by any chance. I guess I will ask him about that as well. I also have borderline diabetes insepidus. And will repeat that test too. I'm glad to see my tetss showing something! For so long it's been "everything looks great" while I have been feeling not even close to great! I had a few things off when I had infectious disease testing done some years back, but at the time I was feeling better than now and the doctor said it's nothing really. One was EBV and the other was IGG3, which was low. My overall IGG is high too, showing allergies, which seem to really act up in an abnormal way with my CFS. Anyone have similar test results or have any info that may be useful for me to share with or ask my doctor?