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High B12 - what to do

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by gapsGirl929, Mar 31, 2015.

  1. gapsGirl929

    gapsGirl929

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    Hi this is the 2nd time my B12 came back high near 1000. Of course doctor doesn't recommend anything. i occasionally get tingling in extremeties, fatigue, and brain fog. Although im not sure if brain fog is from low bodyweight or not. I seem to be doing a little better. I just started to supplement with Thorne's B-complex which has B-6, B-12, & folate.

    How can I get a more accurate B-12 reading? Should I look into 23andme site? Thanks.

    I just started Gaps diet too. I have symptoms of SIBO so malabsorption in the small intestine is probable.
     
  2. Sherpa

    Sherpa Ex-workaholic adrenaline junkie

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    According to this article

    High or very high serum B12 is an indicator for low serum lithium, which can easily be checked by blood test, or hair elements analysis and urine toxic metals and essential elements.
     
    SDSue likes this.
  3. gapsGirl929

    gapsGirl929

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    Thanks for response. What type of blood test tests for low serum lithium?
    I have had a a hair analysis but most of my minerals were fine except low calcium/magnesium ratio, and it showed signs of detox. No heavy metals from the analysis. I have no gotten urine tested though.
     
  4. Crux

    Crux Senior Member

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    Hi;
    From what I've read about SIBO, B12 deficiency can usually occur. There are B12 producing bacteria, B12 utilizing bacteria, and we end up deficient even with normal to high measures.

    If you can treat it with diet, and herbals, that would be the easiest, with the least side-effects.
     
  5. SwanRonson

    SwanRonson Senior Member

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    Which one? They have several.
     
  6. dannybex

    dannybex Senior Member

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    Your b12 can be 'high', but actually functionally low. The test to find out if it's the latter, is the MMA test -- measures methylmalonic acid. RichVank has many posts on this here on PR.

    Tingling or neuropathy can also be a result of low thiamine, and/or caused by even low amounts of b6, which needs sufficient b2 to break it down to it's active form, p5p.
     
  7. drob31

    drob31 Senior Member

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    My High b12 seems to be caused by supplementation. Although I think danny is correct about the functional aspect of it.
     
  8. SwanRonson

    SwanRonson Senior Member

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    If mma and homocysteine are normal, I wouldn't think 900's is a bad thing is it?
     
  9. Gondwanaland

    Gondwanaland Senior Member

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    I think that a homocysteine result (ideal is 6.3) can tell you if all your B12 is being properly used by the cells and Methylmalonic acid by the mitochondria. B12 result on its own is useless.
     
  10. PeterPositive

    PeterPositive Senior Member

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    You may be right about homocysteine, but I am probably an exception to the rule.
    My Hcy level was 13-14 when taking exclusively Ad-B12 (800mcg / day) for months.

    Then I added Methyl-B12, 2000mcg / day. After 3 months my Hcy was 12-13.
    Then I pushed Methyl-B12 to 8000mcg / day. My Hcy was still 12.5, after 6 months

    All other co-factors in place as well, B2, B3, B6, methylfolate, zinc...
    At this point I am baffled. At least by the fact that 4x the dose of B12 doesn't change anything. Nor does adding more or less cofactors.

    I am also questioning how the Hcy labs are accurate. Dr Lynch says that after the blood is drawn it should be immediately refrigerated and spun by the lab otherwise the red cells will continue to release homocysteine.

    I have no idea how my lab handles this situation and if they are reliable. If the testing conditions are different I am not sure how precise these tests are.
     
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  11. Gondwanaland

    Gondwanaland Senior Member

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    @PeterPositive have you at some point focused on B6 supplementation?
     
  12. PeterPositive

    PeterPositive Senior Member

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    I tested for moderately elevated HPL (see signature) so I've been taking between 50 and 70mg of P5P, pretty high dose, but it helps, although it doesn't seem to have any impact on homocysteine.

    Cheers
     
    Gondwanaland likes this.

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