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High B12, Low D, hypothyroid. Is there a connection?

Discussion in 'Diagnostic Guidelines and Laboratory Testing' started by SOC, Feb 8, 2013.

  1. SOC

    SOC Senior Member

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    Daughter and I both have super high B12, which doesn't come down easily even if we stop taking B12. I thought humans excrete excess B12, but we certainly don't seem to be doing so.

    We both also have low D that does not increase easily even with high doses of sublingual D. I have been taking at least 5000 IU daily. In 8 months last year that dose increased my D levels by 20 ng/ml. In the 9th month I cut back to 2500 IU daily and my level dropped 5 ng/ml in a month. :aghhh: Now I'm back to 5000 IU daily, so hopefully we'll stop this downward trend. This looks mighty weird to me, but I don't know much about vitamin D. Anybody have any ideas?

    We're both hypothyroid, too. I have no idea if there's a connection there at all.

    Can anyone bring some insight into this persistent high B12, low D situation?
     
  2. aquariusgirl

    aquariusgirl Senior Member

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    B12 ca be high h in the blood if u r not binding it say because of lack of haptocorrin
    Sorry iPad is making it difficult 2 type
     
  3. rlc

    rlc Senior Member

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    Hi SOC, are you taking Magnesium and other cofactors needed to absorb Vitamin D? This article explains how low magnesium levels can make you vitamin D resistant http://www.vitamindcouncil.org/news-archive/2009/magnesium-and-vitamin-ds-co-factors/

    This article explains more about magnesium and how much you need, etc http://www.vitamindcouncil.org/about-vitamin-d/vitamin-d-cofactors/magnesium/

    What dosage of Vitamin D to take, depends on the size of the person, and if they are overweight, the bigger they are the more they need, recent research estimates that the average healthy person will use 3 to 5 thousand IU a day. So 2500 iu is probably not enough to maintain levels, especially if you are using more vitamin D because you are sick. The vitamin D council recommends 10,000 iu a day, for six months, plus cofactors. My Doctor treated me with a 50,000 iu pill ever week for ten weeks, plus a lot of sunshine!!. Sounds a lot, but iu’s are an incredibly small unit of measure.

    So if you increased your dose a lot you may find, things improve quickly because, the amount you have been on even at 5000ius a day is a lot less then is recommended by many sources.

    However if you haven’t already get calcium levels checked first, as this will show if you have any of the diseases, such as parathyroid tumors, etc, which you should not take Vitamin D with.

    Although the science hasn’t been done yet, there does appear to be a link between low Vitamin D and Hypothyroidism. This article mentions that some research done twenty years ago found a link between them, see http://www.goodhormonehealth.com/VitaminD.pdf

    And this recent article says there is certainly a link between them in mice, see http://www.wellnessresources.com/health/articles/low_vitamin_d_contributes_to_thyroid_problems/

    High B12 levels can be caused by many diseases see http://en.diagnosispro.com/differential_diagnosis-for/vitamin-b12-serum-lab-increased/10103-154.html It would be worth getting your Doctor to look at this list to see if you have any of these conditions. One that stands out because, it is very common is Iron deficiency.

    Hope this helps

    All the best

     
  4. SOC

    SOC Senior Member

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    rlc,
    Thank you SO much! I was feeling completely overwhelmed by all the nutritional information available and how it might all fit together for me. You found exactly what I needed and presented in a clear and easy way. I can't thank you enough! :hug:

    You may be right about the magnesium. I'll check into what's in my current supplements as well as the form to make sure I'm getting enough. I think I'll also increase my vitamin D dosage too, since I'm not a small person. :redface:

    The high B12 is a little concerning, although I think iron deficiency is the most likely. I'll look into all of it further, now that I have some direction.

    I really appreciate the effort you put into helping me with this. :D
     
  5. rlc

    rlc Senior Member

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    Hi SOC, happy to help, hope it leads to a big improvement in your health in the near future!!!!

    All the best
     

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