1. Patients launch a $1.27 million crowdfunding campaign for ME/CFS gut microbiome study.
    Check out the website, Facebook and Twitter. Join in donate and spread the word!
ME/CFS and the Magic of the Canine Factor
There's been plenty of research indicating that having pets is good for your health. I never really noticed any particular benefits to having cats, though that may have had more to do with my cats. They've been fairly indifferent to my presence and we've shared a live-and-let-live...
Discuss the article on the Forums.

Hereditary Cerebral Small Vessel Disease

Discussion in 'Neurological/Neuro-sensory' started by merylg, Nov 26, 2012.

  1. merylg

    merylg Senior Member

    Messages:
    755
    Likes:
    468
    Sydney, NSW, Australia
    The cause of this has been found to be a mutation in the High Temperature Requirement-1 (HTRA1) gene. In the aberrant process, mutant HTRA1s have been shown to lose their protease activity leading to an increase in TGF-Beta family signalling.

    TGF-Beta family signalling defects are associated with scoliosis & alopecia.

    TGF-Beta family signalling defects are also associated with Marfan's/Loey Dietz Syndrome.

    http://www.ncbi.nlm.nih.gov/pubmed/22277429

    Angiotensin 1 Receptor Antagonist...a potential therapeutic...(already in use I believe)

    Wondering how many with ME/CFS have a family history of vascular dementia? This could be part of the picture.

    http://www.ncbi.nlm.nih.gov/pubmed/21301034

    Hmmm...also thought to be associated with degenerative disc disease...
    GracieJ likes this.
  2. alex3619

    alex3619 Senior Member

    Messages:
    6,649
    Likes:
    9,738
    Logan, Queensland, Australia
    Hmmm, interesting. One of my brothers has vascular dementia.
  3. merylg

    merylg Senior Member

    Messages:
    755
    Likes:
    468
    Sydney, NSW, Australia
    My father had this history too.
  4. Countrygirl

    Countrygirl Senior Member

    Messages:
    765
    Likes:
    411
    UK
    My mother has vascular dementia and I have scoliosis, degenerative disc problems and alopecia. My brain scan after one of my stroke-type episodes showed lesions in the right basal ganglia.

    I am not looking forward to the future then. :ill:

See more popular forum discussions.

Share This Page