Hi folks I have chronic Hep B infection, I discovered it in 1991 and I´ve been monitoring the disease since then. I have never developed any sign of active liver disease since the diagnosis and all my antibodies exams show that there is no active viral replication. My viral load is low. I got sick with ME almost three years ago and, like many people here, I have been submitted to all kind of tests and exams, and the results all came normal with the exception of an elevated ANA and high titres of IgG CMV . Some people here might know that Hep B infected patients can develop extra hepatic manifestations of the disease and lately my infectologist has been thinking about treating Hep B infection to see if there is any change in my ME evolution. I did an elastography that showed more liver fibrosis than expected for my viral load so now there is no excuse and I´m going to start an antiviral, Tenofovir. On top of that, there is the question of treating or not CMV . I know that the best antivirals for CMV are toxic for the liver so right now we don´t consider any kind of viral treatment. As soon as I start the drug, i´ll post my observations.