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Help with my detox genetic genie results?

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by jammies, Aug 28, 2013.

  1. jammies

    jammies

    Messages:
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    Hello all;

    I am trying to figure out what my detox data means. I am about to start a mercury detox plan and would like to know if I will face any extra challenges. Or anything that might point to a way to help with this horrible fatigue!! Thanks so much!!

    CYP1A1*2C A4889G TT -/-
    CYP1A1 m3 T3205C TT -/-
    CYP1A1 C2453A GG -/-
    CYP1A2 164A>C CC +/+
    CYP1B1 L432V CG +/-
    CYP1B1 N453S CT +/-
    CYP1B1 R48G -- no call
    CYP2A6*2 1799T>A AA -/-
    CYP2A6*20 II -/-
    CYP2C9*2 C430T CT +/-
    CYP2C9*3 A1075C AA -/-
    CYP2C19*17 CC -/-
    CYP2D6 S486T GG +/+
    CYP2D6 100C>T AG +/-
    CYP2D6 2850C>T AG +/-
    CYP2E1*1B 9896C>G CC -/-
    CYP2E1*1B 10023G>A GG -/-
    CYP2E1*4 4768G>A GG -/-
    CYP3A4*1B TT -/-
    CYP3A4*2 S222P AA -/-
    CYP3A4*3 M445T AA -/-
    CYP3A4*16 T185S GG -/-
    GSTP1 I105V AA -/-
    GSTP1 A114V CC -/-
    SOD2 A16V AG +/-
    NAT1 R187Q GG -/-
    NAT1 R64W CC -/-
    NAT2 I114T CT +/-
    NAT2 R197Q AG +/-
    NAT2 G286E GG -/-
    NAT2 R64Q GG -/-
    NAT2 K268R AG +/-
    Gene Result
    GSTT1 Absent*
  2. Sarah-Mac

    Sarah-Mac

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    Leesburg, Virginia
    I have the GSTT1 absent as well...and it is a big deal. I am still trying to figure out how to supplement for it along with my other methylation pathway mutations. This is the response I got from the MTHFR support facebook page...https://www.facebook.com/mthfrsuppo...ffset=0&total_comments=1&notif_t=feed_comment
    I will keep you posted if and when I figure it out...I see my amazing doc in Nov and he should know...I think he is going to say that I need to do topical glutathione but I am not sure...I guess there is a blood test for it as well...It is the mother of all antioxidants and you and I are missing one of the enzymes to get crap out of our bodies...I think it is a big one...but just like MTHFR, one is worse than the other and I don't know enough about this yet... :thumbsup:
  3. Violeta

    Violeta Senior Member

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    Thanks for that link to the facebook group.:)
  4. jammies

    jammies

    Messages:
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    8

    Wow - that is interesting. Makes me really nervous about this whole chelation thing I'm planning to start next week. Would you mind sharing what your doc says when you see him?

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