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help with genomic results

Discussion in 'Genetic Testing and SNPs' started by cigana, Jul 19, 2013.

  1. cigana

    cigana Senior Member

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    UK
    Hi,
    I tried a couple of years ago to get help understanding my results, with not much luck, hopefully now there is a bit more expertise on this forum. If anybody could help interpret these results, perhaps into yasko format or something else which will help with google searches (the notation of my results seems very rare):

    CYP1A2*C: wtwt
    CYP1A2*F: mtmt
    MTHFR A1298C: AC
    MTHFR C677T: CC
    MTR A2756G: AA
    MTRR A66G: GG

    The lab was "Laboratoire Reunis". Also, how important are the " *C " and " *F " of rthe CYP snp's, what do they signify?

    Thankyou.
     
  2. caledonia

    caledonia

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    Cincinnati, OH, USA
    wt = wild type, which is the type held by most of the population, so that's considered normal
    mt = mutant type

    http://snpedia.com/index.php/Rs762551

    CYP1A2C wtwt
    CYP1A2F mtmt

    These control caffeine metabolizing. If you have CYP1A2C you're a slow metabolizer, if you have CYP1A2F you're a fast metabolizer. However, snpedia says that wild type for this SNP is actually rarer, so it's not normal, it's a mutation. So I'm totally confused as to whether you're a slow or fast caffeine metabolizer.
    -=-=-=-=-=-=

    A1298C +/-
    C677T -/-
    MTR A2756G -/- (I think. Most people have AA, so that would appear to be the wildtype.)
    MTRR A66G +/+

    =-=-=-=

    Hopefully, somebody else can chime in, and confirm or deny.
     
    cigana likes this.

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