@Enigmatic: Just throwing this out there...I have had ongoing bowel issues for some years now. Sometimes symptoms get better, sometimes worse. They got worse when starting Freddd's protocol. Low methylfolate really precipitates my symptoms. My personal opinion is that it may have something to do with some epithelial healing due to long-term damage. Should note that I've never been diagnosed with a bowel disease but have also never pursued a diagnosis. Known problems I have are severe uterine fibroids, which can impinge on everything in the abdominal cavity when they get large and are known to have an effect on the intestines/colon. Additionally, my diet was shite for the entirety of my adult life. I've also wondered a time or two if I might have diverticulitis. Just saying by way of explaining what I mean by "damage" without actually being diagnosed with a bowel syndrome. Early on in the protocol, radically increasing methylfolate helped a lot, per Freddd's paradoxical methylfolate deficiency theory. I've now reduced my methylfolate because in general things have stabilized and it's expensive. LOL I still experience some bowel symptoms occasionally, but because I feel so much better in general on the protocol, I'm riding it out for now. I've seen an overall improvement in my bowels. It's been decades worth of damage so I don't expect it to be healed in six months. I'm fairly pleased with the improvement and hope to see resolution at some point in the future. However, you should approach symptom resolution only in a way that YOU are comfortable with. Good luck. Hope it gets better.