Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Help to buy the Rich protocol.

Discussion in 'Detox: Methylation; B12; Glutathione; Chelation' started by José Segundo, Nov 10, 2016.

  1. Sherpa

    Sherpa Ex-workaholic adrenaline junkie

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    @José Segundo your test looks Good. Maybe you don't have a methylation problem.
     
  2. Learner1

    Learner1 Professional Patient

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    There are a lot of ways to get to a homocysteine of 8... My homocysteine ranges between 3 and 8, and I have methylation issues in abundance.

    Best to have good testing - like a Genova Diagnostics NutrEval and see what's going on. Or RBC folate, methylmalonic acid, MCV, and RBC magnesium could give a sketchy baseline, in addition to homocysteine.

    And look at symptoms of over and undermethylation...
     
  3. JasonUT

    JasonUT Senior Member

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    Hello @José Segundo

    I think you got a great list of Simplified Protocol supplement from others. I wish you luck and good health.

    If finances allow, I also recommend some testing to help provide strategic direction on tailoring your protocol.

    I also recommend a nutrient panel such as Genova NutraEval Plasma or SpectraCell MicroNutrient Panel. My doctors and I guessed for two years straight on what's going on with guidance from Gene SNP interpretations. The nutrient panels helped provide direction and focus. It uncovered the correct co-factors that I needed.

    Also, the Methylation Pathways Panel Extended by HDRI was perhaps the biggest breakthrough as of late. Ordering the "Extended" was key for me, because it gave additional Amino Acid markers Methionine, Cysteine, Cystathionine, Homocysteine, and Taurine. These additional amino acids showed clearly that I am having some Trans-sulfuration issues. Now we are just trying to figure out root-cause and determine correct treatment approach.

    The next tests on my to-do list are Genova Oxidative Stress Analysis 2.0 (Blood) and an HDRI Sulfur Panel. Hopefully, these two panels will provide some more detailed direction on my trans-sulfuration issues.

    I tried to compile a list of tests here. I try to keep this updated as I discover more.

    Again, best of luck.
     
    Learner1 likes this.
  4. Learner1

    Learner1 Professional Patient

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    Getting good data rather than guessing or using a canned protocol is best. You're different than everyone else.

    The NutrEval gives a much wider range of data than the SpectraCell - more stuff tested, better value for what you spend. It also gives some indication of how toxic you are.
     
  5. José Segundo

    José Segundo

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    I attach my vitamin D and mercury results. A few months ago I removed an amalgam and everything went well with Cuttler's protocol.

    Greetings and thanks.
     

    Attached Files:

  6. Learner1

    Learner1 Professional Patient

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  7. Chans

    Chans

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    What are the units for histamine? I got .18 ug/L with a reference of less than 1.00.

    @José Segundo
     
  8. José Segundo

    José Segundo

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    Hi. I am in Spain and getting many things is almost impossible. I can ask iHerb without problem. Is my basket correct for this protocol? meti.PNG

    However, I do not find in Spain or iHerb any of the 2 mentioned multivitamins. Does another serve? Thank you.

    @Learner1 @Sherpa @aaron_c @JasonUT
     
  9. Learner1

    Learner1 Professional Patient

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    I am not familiar with any of those products. I've had issues with toxicity in another KAL product, though, and don't trust their standards. I only use 5-MTHF, not folinic acid.

    You may also need other methylation cofactors, like B2, B6, magnesium, trimethylglycine, amino acids, like glycine, and B1 and molybdenum for the transsulfuration pathway.

    Products from companies I trust and use are:

    Allergy Research or Nutricology NT Factor
    Thorne MethylGuard Plus
    Thorne Neurochondria
    Thorne 5-MTHF
    Thorne Pyridoxal-5-phosphate
    Thorne Riboflavin-5-phosphate

    There are similar products from Seeking Health and Designs for Health that is use if Thorne wasn't available.

    I also do injections of high potency B complex and methylB12. There is a Spanish company that makes high quality MB12, the name behind with F as I recall..
     
  10. José Segundo

    José Segundo

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    Finally I ordered B-Minus at Amazon UK. I think that the iHerb and the B-Minus will arrive next week.

    Is it advisable to start with a quarter of the indicated doses?

    I have the following note of maximum doses, I think it is correct:
    1. B-Minus from 1/4 to 4 daily.
    2. Methyl-B12 2.000 mcg sublingual.
    3. Methyltetrahydrofolate 200 mcg.
    4. Folate 200 mcg.
    5. Lecithin 1200 mg.

    Best regards!
     

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