I posted a while back about symptoms that suggest CFS. I wanted to post again, in the hope that by sharing some recent test/lab values and specific symptoms, some degree of confirmation can be provided and direction on which doctor(s) to consult. Since early childhood I have suffered from a temperamental stomach, chronic anxiety and poor long-term memory. Although I made my way thru college, graduate school and had a good career, I always felt highly anxious -- which is not my personality at all -- and perpetually tired/falling behind. 4-years ago, after feeling completely burned out, I was diagnosed with celiac disease. Unfortunately, strict adherence to a gluten-free diet has actually worsened many symptoms and caused the onset of others. It initially felt like I was going thru withdrawal – which, I gather I was. Follow-up testing have shown that I am faithfully following the diet. Since the celiac diagnosis, I have seen countless doctors, received a few addt’ diagnosis, including hashimoto's disease and autonomic dysreflexia, and have not been able to work full-time. Symptoms: 1) Extremely Debilitating Fatigue: which does not respond to any amount of sleep. I wake up each morning feeling hung over -- disoriented, sore throat, head pressure, stomachache, etc. I typically need to take a monster nap every day, just to sort of function. While sleeping does not necessarily help, the alternative is to stay awake, which often is not possible. 2) Brain Fog: This is somewhat difficult to describe, but it feels as though someone is constantly squeezing my head, with the greatest pressure localized near the temples and motor cortex (upper) region. I also have increasing pressure around my cheek bones and a feeling of fatigue in my jaw. The fog itself registers as considerably slowed processing, forgetful, horrible word retrieval/memory, inability to carry a linear thought/process. Sadly, my productivity has been substantially reduced. Honestly, I"m not sure how anyone can properly function and make a living under these circumstances. Hats off to you if you are! 3) Stomachache: This has been a constant throughout my life, but it's only since going gluten-free that the stomachaches have become downright debilitating. I cannot eat or drink anything without my stomach having fits. I have had many GI tests, most of which have provided no relevant information. Recently, however, my integrative medicine doctor ordered a fecal analysis, which did indicate flora imbalances. I already take a lot of probiotics, so not sure what else I should be doing here? 4) Headache: It's constant and ranges from head pressure, to full-on headache. 5) Heartache: I don't know what to make of this and maybe have been too dismissive. It's just a localized sense of discomfort around the heart, as well as reduced sensation (reduced circulation?) around my left shoulder. Hmm? Maybe I should see a cardiologist? 6) Tremors: My hands exhibit constant mild tremors -- though evidently not consistent with Parkinson's or MS; based on a single consult. Also, I am increasingly aware of full-body tremors. It feels as though my body is vibrating -- I'm most aware when I lay down at night. 7: Increasing joint pain and stiffness. Genetic Tests: Genetic testing revealed that I have a heterozygous mutation of all 3 MTHFR genes, as well as COMT V158M & H62H, both VDR genes, MTRR A66G, and both CBS genes. I also have a homozygous mutation of MAO-A R297R and BHMT 02, 04, 08. Sound like I did NOT hit the genetic lottery jack pot. Lab Tests: Low vitamin-d (though in the 40s/50s w/ 5000 IUs daily); low testosterone; low PTH, elevated TSH & TPO (thyroid); slightly elevated cholesterol and glucose serum; upregulated immune system; out-of-whack neurotransmitters and adrenal fatigue based on a 24-hour adrenal study. Finally, a sleep study suggested that I have mild sleep apnea. This all seems so surreal to me. I knew that I had some seemingly minor health challenges, but it's as if my body has gone off a cliff in the past few years. I'm sure my environment has not helped either: have an active 3-year old son and a perpetually stressed wife who is not taking my situation well at all. And, as a middle-aged male, I feel the added burden of not being able to properly work and provide for my family. All this said, my current stress level, compared to the past few years, is actually quite good -- as I understand now how destructive it can be and make a daily / momemt-by-moment commitment to be as stress-free as possible. Anyhow, any treatment suggestions, type of doctor(s) to consult, words of wisdom, etc is greatly appreciated.