Here is my genetic genie report: Here is what I THINK I have figured out: The snps predict that I might have stomach permeability issues. Which indeed I did have. I think they are gone with a lot of money spent on supplements. The snps also predict that I might have ammonia issues. I have seen some evidence of this in some blood tests and reactions to foods. The pain that I get in between my shoulder blades may be associated with the ammonia problem. It comes and goes for months at a time, it is reduced when I fast and it gets worse when I eat red meat. I should fix my ammonia issues before attempting to go on meb12 and mefolate. Am I right?? Questions on alleles and snps and terminology I have been confused since I opened my genetic report (I have to admit I'm getting better, getting better all the time, can't get much worse). Here are some of my problems: I am starting to understand the orientation but sometimes it seems like the risk allele that is listed in my Sterling report has as the options a C and a G or an A and a T. If the gene in SNPedia is minus orientation, do you always switch A->T, T->A, C->G and G->C? Or are there exceptions? I had thought that +/+ was a homozygous polymorphism on this site but what about the allele's where the rare/wild one is protective? Is the healthier gene the -/- or the rare gene?