What is the difference between histadelia undermethylation (high brain histamine, very common with mental illnesses like depression) and CFSs undermethylation. Both are "undermethylators" right? But the treatment is so different. Histadelia is treated mostly with l-methionine and calcium and magnesium, and to avoid folates (?), where as CFS methylation treatment is familiar from here, methyl b12, methylfolate etc.