Now, I understand that LC:MS amino acid analyses are notoriously unreliable. Despite this, I ordered a 40-item amino acid panel at a local hospital, hoping it would yield (indirect) clues on the state of, i.a., my Trp metabolism, 5HT/DA synthesis, and BCAA availability. Yet there's a reliability complication. After gene analysis revealed I'm C665T homozygenous (double mutation), I had two Homocysteine (Hcy) tests done at two different reputable hospitals, one month apart. The results came back as 69.26 and 68.70 umol/l respectively. (Yikes; I've since begun sublingual methylfolate and methylcobalamin supplementation). The 40-item amino acid assay (attached) was done concurrently with the second Hcy test at the very same hospital. But guess what - the amino panel gives a value of 2.5 uM (?) for Hcy. Unless I'm terribly wrong, this is a massive discrepancy. I'm tempted to write off the 40-acid panel's results wholesale because of it. My questions: - I am correct in detecting this discrepancy, and if so, can I set any store by the amino acid results at all? - Naively assuming that the panel's other values are indeed correct-ish, does anyone's expert eye detect any obvious anomalies? A whole bunch came back with values of 0,0, which I assume is because of measurement problems. The only non-0 that was outside the normal range is a-ABA. Looking forward to your collective insights! J.G.